ArticleThe Journal of comparative neurology2001
Developmental regulation of CPG15 expression in Xenopus.
Article in The Journal of comparative neurology, 2001. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
18 citing papers in PubMed.
- The Role of Neuritin 1 in Synaptic Plasticity and Sensory Nerve Function: Integrator of Neurotrophic, Metabolic and Injury Signals.The European journal of neuroscience · 2026Review
- Neuritin: a multifaceted neuroprotective factor with emerging applications for neurodegeneration.Frontiers in neuroscience · 2025Review
- Article
- CPG15/Neuritin Mimics Experience in Selecting Excitatory Synapses for Stabilization by Facilitating PSD95 Recruitment.Cell reports · 2019Article
- Functions and the related signaling pathways of the neurotrophic factor neuritin.Acta pharmacologica Sinica · 2018Review
- Neuritin 1 expression in human normal tissues and its association with various human cancers.International journal of clinical and experimental pathology · 2018Article
- Recombinant hNeuritin Promotes Structural and Functional Recovery of Sciatic Nerve Injury in Rats.Frontiers in neuroscience · 2016Article
- Neuritin can normalize neural deficits of Alzheimer's disease.Cell death & disease · 2014Article
- Neuritin attenuates cognitive function impairments in tg2576 mouse model of Alzheimer's disease.PloS one · 2014Article
- Activity-regulated genes as mediators of neural circuit plasticity.Progress in neurobiology · 2011Review
- Interaction of survival of motor neuron (SMN) and HuD proteins with mRNA cpg15 rescues motor neuron axonal deficits.Proceedings of the National Academy of Sciences of the United States of America · 2011Article
- The function of activity-regulated genes in the nervous system.Physiological reviews · 2009Review
- Cloning and Phylogenetic Analysis of NMDA Receptor Subunits NR1, NR2A and NR2B in Xenopus laevis Tadpoles.Frontiers in molecular neuroscience · 2009Article
- Androgen regulates neuritin mRNA levels in an in vivo model of steroid-enhanced peripheral nerve regeneration.Journal of neurotrauma · 2008Article
- cpg15 and cpg15-2 constitute a family of activity-regulated ligands expressed differentially in the nervous system to promote neurite growth and neuronal survival.The Journal of comparative neurology · 2008Article
- Motoneuron injury and repair: New perspectives on gonadal steroids as neurotherapeutics.Journal of molecular neuroscience : MN · 2006Review
- Regulation of cpg15 expression during single whisker experience in the barrel cortex of adult mice.Journal of neurobiology · 2005Article
- Regulation of cpg15 by signaling pathways that mediate synaptic plasticity.Molecular and cellular neurosciences · 2003Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
Mechanisms controlling dendritic arbor formation affect the establishment of neuronal circuits. Candidate plasticity gene 15 (CPG15) is a glycosylphosphatidyl inositol (GPI)-linked activity-induced protein that has been shown to function as an intercellular signaling molecule that can promote the morphological and physiological development of the Xenopus retinotectal system. A thorough understanding of CPG15 function requires knowledge of the spatiotemporal expression of the endogenous protein. We therefore cloned Xenopus cpg15 and used RNA in situ hybridization and immunohistochemistry to determine the pattern of CPG15 expression. cpg15 mRNA and CPG15 protein are first detectable in the developing spinal cord and become widespread as development proceeds. CPG15 is expressed in sensory regions of the brain, including the visual, auditory, and olfactory systems. Within the retina, CPG15 is only expressed in retinal ganglion cells. CPG15 protein is concentrated in axon tracts, including retinal axons. These data support a model in which CPG15 expressed in retinal ganglion cells is trafficked to retinal axons, where it modulates postsynaptic dendritic arbor elaboration, and synaptic maturation.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.