SynthesisThe Cochrane database of systematic reviews2001
Interventions for treating constipation in pregnancy.
Synthesis in The Cochrane database of systematic reviews, 2001. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00571896 (The Use of SennaS for Prevention of Post-operative Constipation After Urogynecologic Surgery), which is not on this map. Cited by 9 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Use of SennaS for Prevention of Post-operative Constipation After Urogynecologic Surgery: a Randomized Double Blinded Placebo Controlled Trial
Who cites it
9 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Interventions for treating constipation in pregnancy.The Cochrane database of systematic reviews · 2000Pooled it
- Is a multispecies probiotic mixture effective in constipation during pregnancy? 'A pilot study'.Nutrition journal · 2012Trial
- Gut microbiota in gastrointestinal diseases during pregnancy.World journal of clinical cases · 2022Review
- Increased adiposity, inflammation, metabolic disruption and dyslipidemia in adult male offspring of DOSS treated C57BL/6 dams.Scientific reports · 2019Article
- Effects of Crude Oil/Dispersant Mixture and Dispersant Components on PPARγ Activity in Vitro and in Vivo: Identification of Dioctyl Sodium Sulfosuccinate (DOSS; CAS #577-11-7) as a Probable Obesogen.Environmental health perspectives · 2016Article
- Wheat bran: its composition and benefits to health, a European perspective.International journal of food sciences and nutrition · 2012Review
- A review of the methodological features of systematic reviews in maternal medicine.BMC medicine · 2007Review
- Defecatory symptoms during and after the first pregnancy: prevalences and associated factors.International urogynecology journal and pelvic floor dysfunction · 2006Article
- Article
Corrections and comments
- Update of
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundConstipation is a common problem in late pregnancy. Circulating progesterone may be the cause of slower gastrointestinal movement in mid and late pregnancy.
objectivesThe objective of this review was to assess the effects of different methods for treating constipation in pregnancy. SEARCH STRATEGY: We searched the Cochrane Pregnancy and Childbirth Group trials register, the Cochrane Controlled Trials Register and MEDLINE. Date of last search: January 2001. SELECTION CRITERIA: Randomised trials of any treatment for constipation in pregnancy. DATA COLLECTION AND ANALYSIS: Trial quality assessments and data extraction were done independently by two reviewers. MAIN
resultsTwo suitable trials were identified. Fibre supplements increased the frequency of defecation (odds ratio 0.18, 95% confidence interval 0.05 to 0.67), and lead to softer stools. Stimulant laxatives are more effective than bulk-forming laxatives (odds ratio 0.30, 95% confidence interval 0.14 to 0.61), but may cause more side effects. REVIEWER'S
conclusionsDietary supplements of fibre in the form of bran or wheat fibre are likely to help women experiencing constipation in pregnancy. If the problem fails to resolve, stimulant laxatives are likely to prove more effective.
Indexed as
Identifiers
11405974What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.