ArticlePlant physiology2001
Networking senescence-regulating pathways by using Arabidopsis enhancer trap lines.
Article in Plant physiology, 2001. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 71 papers.
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Who cites it
71 citing papers in PubMed, 240 citations in OpenAlex.
- The old nourishes the new: 100 years of leaf senescence studies in Plant Physiology.Plant physiology · 2026Review
- The loss of COP1 delays senescence and inhibits root growth through modulation of sucrose allocation and availability.Plant physiology · 2026Article
- Genome-wide identification, characterization, evolutionary analysis, and expression profiling of the FCS-like zinc finger (FLZ) gene family in soybean (Glycine max L.) under abiotic stresses.Scientific reports · 2026Article
- A single-base mutation on the 5' UTR of BrATG5 confers the premature leaf senescence phenotype in Chinese cabbage.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2025Article
- Circadian clock regulation in soybean senescence: a transcriptome analysis of early and late senescence types.BMC genomics · 2025Article
- Genome-Wide Identification ofInternational journal of molecular sciences · 2024Article
- ABI5-FLZ13 module transcriptionally represses growth-related genes to delay seed germination in response to ABA.Plant communications · 2023Article
- The ABA-AtNAP-SAG113 PP2C module regulates leaf senescence by dephoshorylating SAG114 SnRK3.25 in Arabidopsis.Molecular horticulture · 2023Article
- Comparative Physiological and Transcriptomic Mechanisms of Defoliation in Cotton in Response to Thidiazuron versus Ethephon.International journal of molecular sciences · 2023Article
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- Dual control of MAPK activities by AP2C1 and MKP1 MAPK phosphatases regulates defence responses in Arabidopsis.Journal of experimental botany · 2022Article
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- Overexpression ofFrontiers in plant science · 2022Article
- Regulation of Arabidopsis Matrix Metalloproteinases by Mitogen-Activated Protein Kinases and Their Function in Leaf Senescence.Frontiers in plant science · 2022Article
- Changes in Polar Metabolites Content during Natural and Methyl-Jasmonate-Promoted Senescence ofInternational journal of molecular sciences · 2021Article
- Sulfuric Acid and Gibberellic Acid (GAThe protein journal · 2021Article
- Genome-wide Identification and Characterization of FCS-Like Zinc Finger (FLZ) Family Genes in Maize (International journal of molecular sciences · 2021Article
- Integrating transcriptomic and metabolomic analysis of hormone pathways in Acer rubrum during developmental leaf senescence.BMC plant biology · 2020Article
- ATBS1-INTERACTING FACTOR 2 negatively regulates dark- and brassinosteroid-induced leaf senescence through interactions with INDUCER OF CBF EXPRESSION 1.Journal of experimental botany · 2020Article
- Signal Transduction in Leaf Senescence: Progress and Perspective.Plants (Basel, Switzerland) · 2019Review
11 more citing papers are in PubMed but not listed here.
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The last phase of leaf development, generally referred to as leaf senescence, is an integral part of plant development that involves massive programmed cell death. Due to a sharp decline of photosynthetic capacity in a leaf, senescence limits crop yield and forest plant biomass production. However, the biochemical components and regulatory mechanisms underlying leaf senescence are poorly characterized. Although several approaches such as differential cDNA screening, differential display, and cDNA subtraction have been employed to isolate senescence-associated genes (SAGs), only a limited number of SAGs have been identified, and information regarding the regulation of these genes is fragmentary. Here we report on the utilization of enhancer trap approach toward the identification and analysis of SAGs. We have developed a sensitive large-scale screening method and have screened 1,300 Arabidopsis enhancer trap lines and have identified 147 lines in which the reporter gene GUS (beta-glucuronidase) is expressed in senescing leaves but not in non-senescing ones. We have systematically analyzed the regulation of beta-glucuronidase expression in 125 lines (genetically, each contains single T-DNA insertion) by six senescence-promoting factors, namely abscisic acid, ethylene, jasmonic acid, brassinosteroid, darkness, and dehydration. This analysis not only reveals the complexity of the regulatory circuitry but also allows us to postulate the existence of a network of senescence-promoting pathways. We have also cloned three SAGs from randomly selected enhancer trap lines, demonstrating that reporter expression pattern reflects the expression pattern of the endogenous gene.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.