Evidence map›Paper›PMID 11390659›Full record

ArticleMolecular and cellular biology2001

Essential roles of Snf5p in Snf-Swi chromatin remodeling in vivo.

F Geng, Y Cao, B C Laurent

Open access · greenAbstract read
In one paragraph

Article in Molecular and cellular biology, 2001. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 58 citations in OpenAlex.

  1. Review
  2. MoSnf5 Regulates Fungal Virulence, Growth, and Conidiation inJournal of fungi (Basel, Switzerland) · 2022
    Article
  3. Review
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  9. Acetyl-CoA carboxylase regulates global histone acetylation.The Journal of biological chemistry · 2012
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 2 countries.

F GengDepartment of Microbiology and Immunology and Morse Institute of Molecular Biology and Genetics, State University of New York, Brooklyn, New York 11203, USA.
Y Cao
B C Laurent
State University of New York · US

Funding

CELL CYCLE PROGRESSION AND CHROMATIN REMODELING IN YEASTR01GM056700 · NIGMS · SUNY DOWNSTATE MEDICAL CENTER · PI LAURENT, BREHON C · 1998 to 2007
$1.9M
NIGMS NIH HHS GM56700NIGMS NIH HHS R01 GM056700
6 · The paper itself

Abstract

Snf-Swi, the prototypical ATP-dependent nucleosome-remodeling complex, regulates transcription of a subset of yeast genes. With the exception of Snf2p, the ATPase subunit, the functions of the other components are unknown. We have investigated the role of the conserved Snf-Swi core subunit Snf5p through characterization of two conditional snf5 mutants. The mutants contain single amino acid alterations of invariant or conserved residues that abolish Snf-Swi-dependent transcription by distinct mechanisms. One mutation impairs Snf-Swi assembly and, consequently, its stable association with a target promoter. The other blocks a postrecruitment catalytic remodeling step. These findings suggest that Snf5p coordinates the assembly and nucleosome-remodeling activities of Snf-Swi.

Indexed as

Adenosine TriphosphateAllelesAmino Acid Motifsbeta-FructofuranosidaseChromatinChromosomal Proteins, Non-HistoneDNADNA-Binding ProteinsGenes, ReporterGlucoseGlycoside HydrolasesHumansImmunoblottingMacromolecular SubstancesNucleosomesPromoter Regions, GeneticAdenosine Triphosphatebeta-FructofuranosidaseChromatinChromosomal Proteins, Non-HistoneDNADNA-Binding ProteinsGlucoseGlycoside HydrolasesMacromolecular SubstancesNucleosomesRecombinant Fusion ProteinsSaccharomyces cerevisiae ProteinsSMARCB1 ProteinSMARCB1 protein, humanSNF5 protein, S cerevisiaeTranscription Factors

Identifiers

PMID11390659
PMCPMC87091
OpenAlexW2148594364

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.