GuidelineAnnals of emergency medicine2001
Principles of appropriate antibiotic use for treatment of uncomplicated acute bronchitis: background.
Guideline in Annals of emergency medicine, 2001. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07030855 (Assessing the Efficacy of Elixirium Thymi Compositum in the Treatment of Acute Bronchitis in Pediatric Patients), which is not on this map. Cited by 17 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Assessing the Efficacy of Elixirium Thymi Compositum in the Treatment of Acute Bronchitis in Pediatric Patients (EXOTIC): A Double-blind, Randomized, Placebo-controlled, Phase 4 Study
Who cites it
17 citing papers in PubMed, 39 citations in OpenAlex.
- Amoxicillin for acute lower respiratory tract infection in primary care: subgroup analysis of potential high-risk groups.The British journal of general practice : the journal of the Royal College of General Practitioners · 2014Trial
- Access to a polymerase chain reaction assay method targeting 13 respiratory viruses can reduce antibiotics: a randomised, controlled trial.BMC medicine · 2011Trial
- Effect of antibiotic prescribing strategies and an information leaflet on longer-term reconsultation for acute lower respiratory tract infection.The British journal of general practice : the journal of the Royal College of General Practitioners · 2009Trial
- Expert opinion and clinical practice recommendations using a modified Delphi approach for pediatric acute cough evaluation and management in India.Lung India : official organ of Indian Chest Society · 2026Article
- (Fluoro)quinolone prescriptions for upper respiratory tract infections in the German outpatient sector: a health insurance claims analysis.GMS infectious diseases · 2025Article
- Impact of Antibiotics Used for Acute Aspiration Bronchitis on the Prevention of Pneumonia.Geriatrics (Basel, Switzerland) · 2024Article
- Guidelines on Implementing Antimicrobial Stewardship Programs in Korea.Infection & chemotherapy · 2021Review
- Patient and provider characteristics and outcomes associated with outpatient antibiotic overuse in acute adult bronchitis.Proceedings (Baylor University. Medical Center) · 2020Article
- Prescription of antibacterial agents for acute upper respiratory tract infections in Beijing, 2010-2012.European journal of clinical pharmacology · 2016Article
- The Value of Macrolide-Based Regimens for Community-Acquired Pneumonia.Current infectious disease reports · 2015Article
- Article
- Fever and the rational use of antimicrobials in the emergency department.Emergency medicine clinics of North America · 2013Review
- Visit complexity, diagnostic uncertainty, and antibiotic prescribing for acute cough in primary care: a retrospective study.BMC family practice · 2013Article
- Antimicrobial, Antiviral and Immunomodulatory Activity Studies of Pelargonium sidoides (EPsPharmaceuticals (Basel, Switzerland) · 2011Review
- Acute respiratory infections in persons with spinal cord injury.Physical medicine and rehabilitation clinics of North America · 2007Review
- Management of acute bronchitis in healthy adults.Infectious disease clinics of North America · 2004Review
- Acute bronchitis: state of the art diagnosis and therapy.Comprehensive therapy · 2004Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 1 institution in 1 country.
Funding
Abstract
The following principles of appropriate antibiotic use for adults with acute bronchitis apply to immunocompetent adults without complicating comorbid conditions, such as chronic lung or heart disease. The evaluation of adults with an acute cough illness or a presumptive diagnosis of uncomplicated acute bronchitis should focus on ruling out serious illness, particularly pneumonia. In healthy, nonelderly adults, pneumonia is uncommon in the absence of vital sign abnormalities or asymmetrical lung sounds, and chest radiography is usually not indicated. In patients with cough lasting 3 weeks or longer, chest radiography may be warranted in the absence of other known causes. Routine antibiotic treatment of uncomplicated acute bronchitis is not recommended, regardless of duration of cough. If pertussis infection is suspected (an unusual circumstance), a diagnostic test should be performed and antimicrobial therapy initiated. Patient satisfaction with care for acute bronchitis depends most on physician--patient communication rather than on antibiotic treatment.
Indexed as
Identifiers
11385346PMC7132523W2163762472What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.