Evidence map›Paper›PMID 11353084›Full record

ArticleNucleic acids research2001

The complete genome sequence of the murine respiratory pathogen Mycoplasma pulmonis.

I Chambaud, R Heilig, S Ferris, V Barbe, D Samson, F Galisson, I Moszer, K Dybvig, H Wróblewski, A Viari and 2 more

Open access · bronzeAbstract read
In one paragraph

Article in Nucleic acids research, 2001. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 96 papers.

0numbers the graph read from it
0cells of the map it votes in
96citing papers in PubMed
24.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

96 citing papers in PubMed, 279 citations in OpenAlex.

  1. Article
  2. Pathogenic mechanisms and vaccine development forFrontiers in microbiology · 2025
    Review
  3. The complete genome sequence of unculturableFrontiers in cellular and infection microbiology · 2024
    Article
  4. Article
  5. Article
  6. Review
  7. Review
  8. NOD2/c-Jun NHJournal of bacteriology · 2020
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Cathepsin L protects mice from mycoplasmal infection and is essential for airway lymphangiogenesis.American journal of respiratory cell and molecular biology · 2013
    Article
  18. Article
  19. CpG underrepresentation and the bacterial CpG-specific DNA methyltransferase M.MpeI.Proceedings of the National Academy of Sciences of the United States of America · 2013
    Article
  20. Article

36 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

I ChambaudINRA-Université de Bordeaux 2, Institut de Biologie Végétale Moléculaire, 71 avenue Edouard Bourleaux, BP 81, 33883 Villenave D'Ornon Cedex, France.
R Heilig
S Ferris
V Barbe
D Samson
F Galisson
I Moszer
K Dybvig
H Wróblewski
A Viari
E P Rocha
A Blanchard
Laboratoire Génome et Développement des Plantes · FR

Funding

Antigenic Variation in MycoplasmasR21AI041113 · NIAID · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI DYBVIG, KEVIN F · 2004 to 2004
$337k
ANTIGENIC VARIATION IN MYCOPLASMASR01AI041113 · NIAID · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI DYBVIG, KEVIN F · 1997 to 2000
$200k
NIAID NIH HHS AI41113NIAID NIH HHS R01 AI041113NIAID NIH HHS R21 AI041113
6 · The paper itself

Abstract

Mycoplasma pulmonis is a wall-less eubacterium belonging to the Mollicutes (trivial name, mycoplasmas) and responsible for murine respiratory diseases. The genome of strain UAB CTIP is composed of a single circular 963 879 bp chromosome with a G + C content of 26.6 mol%, i.e. the lowest reported among bacteria, Ureaplasma urealyticum apart. This genome contains 782 putative coding sequences (CDSs) covering 91.4% of its length and a function could be assigned to 486 CDSs whilst 92 matched the gene sequences of hypothetical proteins, leaving 204 CDSs without significant database match. The genome contains a single set of rRNA genes and only 29 tRNAs genes. The replication origin oriC was localized by sequence analysis and by using the G + C skew method. Sequence polymorphisms within stretches of repeated nucleotides generate phase-variable protein antigens whilst a recombinase gene is likely to catalyse the site-specific DNA inversions in major M.pulmonis surface antigens. Furthermore, a hemolysin, secreted nucleases and a glyco-protease are predicted virulence factors. Surprisingly, several of the genes previously reported to be essential for a self-replicating minimal cell are missing in the M.pulmonis genome although this one is larger than the other mycoplasma genomes fully sequenced until now.

Indexed as

GenomeAnimalsAntigens, BacterialBase CompositionCodon, TerminatorComputational BiologyEvolution, MolecularGenetic CodeGenomic LibraryHumansInternetLipoproteinsMiceMolecular Sequence DataMutationMycoplasmaAntigens, BacterialCodon, TerminatorLipoproteinsRNA, Bacterial

Identifiers

PMID11353084
PMCPMC55444
OpenAlexW2168669146

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.