ArticleJournal of neuro-oncology2001
Intracranial Ewing sarcoma/'peripheral' primitive neuroectodermal tumor of dural origin with molecular genetic confirmation.
Article in Journal of neuro-oncology, 2001. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it, 58 citations in OpenAlex.
- What's in a name? Intracranial peripheral primitive neuroectodermal tumors and CNS primitive neuroectodermal tumors are not the same.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2013Pooled it
- Diagnosis, treatment, and postoperative follow-up of intracranial Ewing sarcoma (EWS): a case report.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2026Article
- Primary intracranial peripheral primitive neuroectodermal tumor: lessons from an exceptionally rare neoplasm. Illustrative case.Journal of neurosurgery. Case lessons · 2024Article
- Primary, Dural-based, Ewing sarcoma in a pediatric patient: presentation of a rare tumor entity with literature review.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2023Review
- Primary intracranial Ewing sarcoma/ peripheral primitive neuroectodermal tumor, an entity of unacquaintance: a series of 8 cases.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2021Article
- Intracranial Ewing Sarcoma - A case report.Surgical neurology international · 2020Article
- Primary intracranial extraosseous Ewing's sarcoma.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2019Article
- Synthetic treatment of intracranial peripheral primitive neuroectodermal tumor with multiple metastasis: a case report.OncoTargets and therapy · 2016Article
- Primary Ewing sarcoma of the cavernous sinus.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2015Article
- Primary intracranial Ewing's sarcoma with unusual features.International journal of clinical and experimental pathology · 2015Article
- [Shoulder girdle, AC and SC joints].Operative Orthopadie und Traumatologie · 2014Article
- Ewing sarcoma of the posterior fossa in an adolescent girl.Case reports in medicine · 2014Article
- Disseminated Intracranial Ewing's Sarcoma in an Adult: A Rare and Difficult Diagnosis.Case reports in oncology · 2012Article
- Ewing's Sarcoma/Peripheral Primitive Neuroectodermal Tumor in the Cerebellopontine Angle : Diagnosis and Treatment.Journal of Korean Neurosurgical Society · 2011Article
- Primary extraosseous intracranial Ewing's sarcoma: Case report and literature review.Indian journal of medical and paediatric oncology : official journal of Indian Society of Medical & Paediatric Oncology · 2011Article
- Central nervous system extraosseous Ewing sarcoma: radiologic manifestations of this newly defined pathologic entity.AJNR. American journal of neuroradiology · 2006Review
- Intracranial peripheral primitive neuroectodermal tumor manifesting as abducens nerve palsy.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2005Article
- Meningeal tumors of childhood and infancy. An update and literature review.Brain pathology (Zurich, Switzerland) · 2003Review
- Primitive neuroectodermal tumors/medulloblastoma.Current neurology and neuroscience reports · 2002Review
- Primary intracranial dural-based Ewing sarcoma/peripheral primitive neuroectodermal tumor mimicking a meningioma: A rare tumor with review of literature.Asian journal of neurosurgeryReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 5 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Ewing sarcoma/'peripheral' primitive neuroectodermal tumor (ES/pPNET) is the designation given to a family of small cell neoplasms that typically arise in bone or soft tissue and are unified by their common expression of the MIC2 antigen and specific translocations involving a gene on chromosome 22q12 [the most common being t(11;22)(q24;q12)]. ES/pPNET of intracranial origin is extraordinary. We report the case of a 6-year-old boy with a large left frontal region mass that adhered to dura and was extracerebral at surgery. Histologic study revealed a high-grade, undifferentiated-appearing neoplasm of small cell type that was negative on immunostudy for glial fibrillary acidic protein, synaptophysin, desmin, leukocyte common antigen, smooth muscle actin and epithelial membrane antigen, but positive for vimentin and neuron-specific enolase and diffusely labeled by antibody O13 (which recognizes the MIC2 gene product). RNA-based polymerase chain reaction assay confirmed the diagnosis of ES/pPNET by demonstrating fusion transcripts indicative of t(11;22) translocation. Bone scan, computerized tomography of the chest and bone marrow examination revealed no systemic tumor. The limited observations published to date suggest that primary intracranial ES/pPNET is most likely to present in childhood as a circumscribed, contrast-enhancing and dural-based extracerebral mass. It must be distinguished from a variety of small cell neoplasms, particularly PNETs of central neuroepithelial origin.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.