ArticleInfection and immunity2001
gp96-peptide vaccination of mice against intracellular bacteria.
Article in Infection and immunity, 2001. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed, 63 citations in OpenAlex.
- Immunosurveillance of cancer and the heat shock protein-CD91 pathway.Cellular immunology · 2019Article
- Article
- A novel tuberculosis antigen identified from human tuberculosis granulomas.Molecular & cellular proteomics : MCP · 2015Article
- Comparative evaluation of booster efficacies of BCG, Ag85B, and Ag85B peptides based vaccines to boost BCG induced immunity in BALB/c mice: a pilot study.Clinical and experimental vaccine research · 2015Article
- Functions of heat shock proteins in pathways of the innate and adaptive immune system.Journal of immunology (Baltimore, Md. : 1950) · 2014Review
- Establishment of tumor-associated immunity requires interaction of heat shock proteins with CD91.Cancer immunology research · 2014Article
- Heat shock protein 70 kDa (HSP70) increase in sea bass (Dicentrarchus labrax, L 1758) thymus after vaccination against Listonella anguillarum.Fish physiology and biochemistry · 2013Article
- Heat shock proteins: stimulators of innate and acquired immunity.BioMed research international · 2013Review
- A role for the heat shock protein-CD91 axis in the initiation of immune responses to tumors.Immunologic research · 2011Article
- Gp96 rich lysate as a vaccine candidate against infection with Salmonella typhimurium.Iranian journal of microbiology · 2010Article
- DNA immunization as an efficient strategy for vaccination.Avicenna journal of medical biotechnology · 2009Article
- Increased proteolysis of diphtheria toxin by human monocytes after heat shock: a subsidiary role for heat-shock protein 70 in antigen processing.Immunology · 2007Article
- Essential role of CD91 in re-presentation of gp96-chaperoned peptides.Proceedings of the National Academy of Sciences of the United States of America · 2004Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This work demonstrates that gp96 preparations isolated from cells infected with intracellular bacteria induce cytotoxic T-lymphocyte responses and confer protection. Our findings extend previous reports on the immunogenicity of gp96-associated peptides to antigens derived from intracellular bacteria. Immunization with gp96 may therefore represent a promising vaccination strategy against bacterial pathogens.
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Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.