ArticleInfection and immunity2001
Gene fragments distinguishing an epidemic-associated strain from a virulent prototype strain of Listeria monocytogenes belong to a distinct functional subset of genes and partially cross-hybridize with other Listeria species.
Article in Infection and immunity, 2001. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed.
- Using MALDI-TOF spectra in epidemiological surveillance for the detection of bacterial subgroups with a possible epidemic potential.BMC infectious diseases · 2021Article
- Insights Into Subspecies Discrimination Potentiality From Bacteria MALDI-TOF Mass Spectra by Using Data Mining and Diversity Studies.Frontiers in microbiology · 2020Article
- Conservation of genomic localization and sequence content of Sau3AI-like restriction-modification gene cassettes among Listeria monocytogenes epidemic clone I and selected strains of serotype 1/2a.Applied and environmental microbiology · 2010Article
- DNA probes for unambiguous identification of Listeria monocytogenes epidemic clone II strains.Applied and environmental microbiology · 2010Article
- Listeriolysin S, a novel peptide haemolysin associated with a subset of lineage I Listeria monocytogenes.PLoS pathogens · 2008Article
- Multiple-locus variable-number tandem-repeat analysis as a tool for subtyping Listeria monocytogenes strains.Journal of clinical microbiology · 2008Article
- Multiplex PCR for simultaneous detection of bacteria of the genus Listeria, Listeria monocytogenes, and major serotypes and epidemic clones of L. monocytogenes.Applied and environmental microbiology · 2007Article
- A single-nucleotide-polymorphism-based multilocus genotyping assay for subtyping lineage I isolates of Listeria monocytogenes.Applied and environmental microbiology · 2007Article
- Conserved genes in a path from commensalism to pathogenicity: comparative phylogenetic profiles of Staphylococcus epidermidis RP62A and ATCC12228.BMC genomics · 2006Article
- Functional consequences of genome evolution in Listeria monocytogenes: the lmo0423 and lmo0422 genes encode sigmaC and LstR, a lineage II-specific heat shock system.Journal of bacteriology · 2005Article
- Truncated internalin A and asymptomatic Listeria monocytogenes carriage: in vivo investigation by allelic exchange.Infection and immunity · 2005Article
- Intraspecific phylogeny and lineage group identification based on the prfA virulence gene cluster of Listeria monocytogenes.Journal of bacteriology · 2004Article
- Epidemic clone I-specific genetic markers in strains of Listeria monocytogenes serotype 4b from foods.Applied and environmental microbiology · 2004Article
- Natural atypical Listeria innocua strains with Listeria monocytogenes pathogenicity island 1 genes.Applied and environmental microbiology · 2004Article
- Genetic markers unique to Listeria monocytogenes serotype 4b differentiate epidemic clone II (hot dog outbreak strains) from other lineages.Applied and environmental microbiology · 2004Article
- New aspects regarding evolution and virulence of Listeria monocytogenes revealed by comparative genomics and DNA arrays.Infection and immunity · 2004Article
- Genome diversification in phylogenetic lineages I and II of Listeria monocytogenes: identification of segments unique to lineage II populations.Journal of bacteriology · 2003Article
- Development of a Listeria monocytogenes EGDe partial proteome reference map and comparison with the protein profiles of food isolates.Applied and environmental microbiology · 2003Article
- Expression of truncated Internalin A is involved in impaired internalization of some Listeria monocytogenes isolates carried asymptomatically by humans.Infection and immunity · 2003Article
- Mixed-genome microarrays reveal multiple serotype and lineage-specific differences among strains of Listeria monocytogenes.Journal of clinical microbiology · 2003Article
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Abstract
Most major food-borne outbreaks of listeriosis in Europe and in the United States have been caused by genetically closely related Listeria monocytogenes strains of serotype 4b. In order to assess whether genomic loci exist that could underlie this increased epidemic potential, we subtracted the genome of the virulent prototype L. monocytogenes strain EGD from a prototype epidemic strain. A total of 39 DNA fragments corresponding to 20% of an estimated total of 150 to 190 kb of differential genome material were isolated. For 21 of these fragments, no function on the basis of homology could be predicted. Of the remaining 18 fragments, 15 had homologies to bacterial surface proteins, some of which have been implicated in virulence mechanisms such as cell invasion, adhesion, or immune escape. Southern hybridization of arrays containing the epidemic-clone-specific DNA segments with genomic DNA of different L. monocytogenes strains was consistent with the current lineage division. Surprisingly, however, some of the fragments hybridized in a mosaic-like fashion to genomes of two other Listeria species, the animal pathogen L. ivanovii and the nonpathogen L. innocua. Taken together, our results provide a starting point for the identification of epidemic-trait-associated genes.
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