ArticleFolia microbiologica2000
The in vitro effect of imipenem and ofloxacin on enzymic activity of Klebsiella strains.
Article in Folia microbiologica, 2000. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
2 citing papers in PubMed, 4 citations in OpenAlex.
- Some properties of Plesiomonas shigelloides treated with aminoglycosides.Folia microbiologica · 2003Article
- Influence on Enterobacter cloacae metabolism, cell-surface hydrophobicity and motility of suprainhibitory concentrations of carbapenems.Folia microbiologica · 2001Article
Corrections and comments
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Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Fifty seven Klebsiella strains, viz. K. pneumoniae (28), K. planticola (19), K. oxytoca (6), K. ornithinolytica (3) and K. terrigena (1) possessed lipolytic and urealytic activity. The effect of imipenem and ofloxacin at subinhibitory concentrations (sub-MICs) on these enzymic activities of 4 strains was studied. At all the concentrations tested (mainly at 1/4 of the MICs) imipenem enhanced lipase activity manifested by cleavage of the substrate Tween 20. The effect of ofloxacin was strain- and concentration-dependent but in most cases lipolytic activity was also increased. The antibiotics practically did not affect the urease activity of the strains.
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