ArticleThe Plant cell2001
Hyperosmotic stress induces the rapid phosphorylation of a soybean phosphatidylinositol transfer protein homolog through activation of the protein kinases SPK1 and SPK2.
Article in The Plant cell, 2001. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers.
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Who cites it
50 citing papers in PubMed, 110 citations in OpenAlex.
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- Comparative transcriptomic and biochemical analyses reveal candidate regulatory genes associated with early drought response signatures in contrasting rapeseed (Brassica napus) cultivars.Scientific reports · 2025Article
- Genome-wide identification of the Sec14 gene family and the response to salt and drought stress in soybean (Glycine max).BMC genomics · 2025Article
- Uncovering tomato candidate genes associated with drought tolerance using Solanum pennellii introgression lines.PloS one · 2023Article
- Linking genome wide RNA sequencing with physio-biochemical and cytological responses to catalogue key genes and metabolic pathways for alkalinity stress tolerance in lentil (Lens culinaris Medikus).BMC plant biology · 2022Article
- Growth Promotion or Osmotic Stress Response: How SNF1-Related Protein Kinase 2 (SnRK2) Kinases Are Activated and Manage Intracellular Signaling in Plants.Plants (Basel, Switzerland) · 2021Review
- Role of Raf-like kinases in SnRK2 activation and osmotic stress response in plants.Nature communications · 2020Review
- Genome-wide survey of sucrose non-fermenting 1-related protein kinase 2 in Rosaceae and expression analysis of PbrSnRK2 in response to ABA stress.BMC genomics · 2020Article
- SnRK2 Protein Kinases and mRNA Decapping Machinery Control Root Development and Response to Salt.Plant physiology · 2020Article
- Genome-Wide Association Study of Topsoil Root System Architecture in Field-Grown Soybean [Frontiers in plant science · 2020Article
- Genome-wide identification, phylogeny, and expression analysis of Sec14-like PITP gene family in sugarcane.Plant cell reports · 2019Article
- The sucrose non-fermenting-1-related protein kinases SAPK1 and SAPK2 function collaboratively as positive regulators of salt stress tolerance in rice.BMC plant biology · 2018Article
- Transcriptome profiling of fully open flowers in a frost-tolerant almond genotype in response to freezing stress.Molecular genetics and genomics : MGG · 2018Article
- Genome-Wide Identification and Characterization of the GmSnRK2 Family in Soybean.International journal of molecular sciences · 2017Article
- Visualization of Phosphatidylinositol 3,5-Bisphosphate Dynamics by a Tandem ML1N-Based Fluorescent Protein Probe in Arabidopsis.Plant & cell physiology · 2017Article
- Genome-wide identification and characterization of SnRK2 gene family in cotton (Gossypium hirsutum L.).BMC genetics · 2017Article
- Sucrose non-ferment 1 related protein kinase 2 (SnRK2) genes could mediate the stress responses in potato (Solanum tuberosum L.).BMC genetics · 2017Article
- Insights into the function of the phasiRNA-triggering miR1514 in response to stress in legumes.Plant signaling & behavior · 2017Article
- Sec14-like phosphatidylinositol transfer proteins and the biological landscape of phosphoinositide signaling in plants.Biochimica et biophysica acta · 2016Review
- Isolation and functional characterization of a cold responsive phosphatidylinositol transfer-associated protein, ZmSEC14p, from maize (Zea may L.).Plant cell reports · 2016Article
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Although phosphatidylinositol transfer proteins (PITPs) are known to serve critical functions in regulating a varied array of signal transduction processes in animals and yeast, the discovery of a similar class of proteins in plants occurred only recently. Here, we report the participation of Ssh1p, a soybean PITP-like protein, in the early events of osmosensory signal transduction in plants, a function not attributed previously to animal or yeast PITPs. Exposure of plant tissues to hyperosmotic stress led to the rapid phosphorylation of Ssh1p, a modification that decreased its ability to associate with membranes. An osmotic stress-activated Ssh1p kinase activity was detected in several plant species by presenting recombinant Ssh1p as a substrate in in-gel kinase assays. Elements of a similar osmosensory signaling pathway also were conserved in yeast, an observation that facilitated the identification of soybean protein kinases SPK1 and SPK2 as stress-activated Ssh1p kinases. This study reveals the activation of SPK1 and/or SPK2 and the subsequent phosphorylation of Ssh1p as two early successive events in a hyperosmotic stress-induced signaling cascade in plants. Furthermore, Ssh1p is shown to enhance the activities of a plant phosphatidylinositol 3-kinase and phosphatidylinositol 4-kinase, an observation that suggests that the ultimate function of Ssh1p in cellular signaling is to alter the plant's capacity to synthesize phosphoinositides during periods of hyperosmotic stress.
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