ArticleThe Plant cell2001
Small changes in the regulation of one Arabidopsis profilin isovariant, PRF1, alter seedling development.
Article in The Plant cell, 2001. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed, 69 citations in OpenAlex.
- An integrated QTL and RNA-seq analysis revealed new petal morphology loci in Brassica napus L.Biotechnology for biofuels and bioproducts · 2024Article
- Actin depolymerizing factor ADF7 inhibits actin bundling protein VILLIN1 to regulate root hair formation in response to osmotic stress in Arabidopsis.PLoS genetics · 2022Article
- Bundling up the Role of the Actin Cytoskeleton in Primary Root Growth.Frontiers in plant science · 2021Review
- GLABRA2 Regulates Actin Bundling Protein VILLIN1 in Root Hair Growth in Response to Osmotic Stress.Plant physiology · 2020Article
- Gene encoding vesicle-associated membrane protein-associated protein from Triticum aestivum (TaVAP) confers tolerance to drought stress.Cell stress & chaperones · 2018Article
- Comparative proteomic study of Arabidopsis mutants mpk4 and mpk6.Scientific reports · 2016Article
- Domestication-driven Gossypium profilin 1 (GhPRF1) gene transduces early flowering phenotype in tobacco by spatial alteration of apical/floral-meristem related gene expression.BMC plant biology · 2016Article
- Profilin-Dependent Nucleation and Assembly of Actin Filaments Controls Cell Elongation in Arabidopsis.Plant physiology · 2016Article
- Arabidopsis plants deficient in constitutive class profilins reveal independent and quantitative genetic effects.BMC plant biology · 2015Article
- Overexpression of profilin 3 affects cell elongation and F-actin organization in Arabidopsis thaliana.Plant cell reports · 2013Article
- High throughput generation of promoter reporter (GFP) transgenic lines of low expressing genes in Arabidopsis and analysis of their expression patterns.Plant methods · 2010Article
- Profilin is essential for tip growth in the moss Physcomitrella patens.The Plant cell · 2007Article
- Class-specific interaction of profilin and ADF isovariants with actin in the regulation of plant development.The Plant cell · 2007Article
- The late pollen actins are essential for normal male and female development in Arabidopsis.Plant molecular biology · 2006Article
- Distinct roles of the first introns on the expression of Arabidopsis profilin gene family members.Plant physiology · 2006Article
- Article
- Genomic characterization and linkage mapping of the apple allergen genes Mal d 2 (thaumatin-like protein) and Mal d 4 (profilin).TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2005Article
- New views on the plant cytoskeleton.Plant physiology · 2004Review
- The role of the actin cytoskeleton in plant cell signaling.The New phytologist · 2004Review
- The putative Arabidopsis arp2/3 complex controls leaf cell morphogenesis.Plant physiology · 2003Article
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
Profilin (PRF) is a low-molecular-weight actin binding protein encoded by a diverse gene family in plants. Arabidopsis PRF1 transcripts are moderately well expressed in all vegetative organs. A regulatory mutant in PRF1, prf1-1, was isolated from a library of T-DNA insertions. The insertion disrupted the promoter region of PRF1 100 bp upstream from the transcriptional start site. Although steady state levels of PRF1 transcripts appeared normal in mature prf1-1 plants, the levels in young seedlings were only one-half those observed in wild type. Reactions with a PRF1 isovariant-specific monoclonal antiserum and general anti-profilin antisera demonstrated that PRF1 protein levels also were one-half those found in wild-type seedlings, although total profilin levels were unaffected. Mutant seedlings no longer could downregulate PRF1 levels in the light, as did wild type. Consistent with their molecular phenotypes, young mutant seedlings displayed several morphological phenotypes but developed into apparently normal adult plants. Their initial germination rate and development were slow, and they produced excessive numbers of root hairs. Mutant seedlings had abnormally raised cotyledons, elongated hypocotyls, and elongated cells in the hypocotyl, typical of phenotypes associated with some defects in light and circadian responses. A wild-type PRF1 transgene fully complements the hypocotyl phenotypes in the prf1-1 mutant. The ability of profilin to regulate actin polymerization and participate directly in signal transduction pathways is discussed in light of the prf1-1 phenotypes.
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