Evidence map›Paper›PMID 11333931›Full record

ArticleJournal of virology2001

Feline immunodeficiency virus cell entry.

S C Frey, E A Hoover, J I Mullins

Abstract read
In one paragraph

Article in Journal of virology, 2001. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. FIV and neuroAIDS.Journal of neurovirology · 2002
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

S C FreyDepartment of Microbiology, University of Washington, Seattle, Washington 98195, USA.
E A Hoover
J I Mullins

Funding

PATHOGENESIS OF FELINE IMMUNODEFICIENCY VIRUS INFECTIONR01AI033773 · NIAID · COLORADO STATE UNIVERSITY-FORT COLLINS · PI HOOVER, EDWARD ARTHUR · 1993 to 2008
$2.6M
NCI NIH HHS CA590402NIAID NIH HHS AI33773NIAID NIH HHS R01 AI033773
6 · The paper itself

Abstract

The process of feline immunodeficiency virus (FIV) cell entry was examined using assays for virus replication intermediates. FIV subtype B was found to utilize the chemokine receptor CXCR4, but not CCR5, as a cellular receptor. Zidovudine blocked formation of late viral replication products most effectively, including circular DNA genome intermediates. Our findings extend the role of CXCR4 as a primary receptor for CD4-independent cell entry by FIV.

Indexed as

AnimalsCell LineImmunodeficiency Virus, FelineReceptors, CXCR4Receptors, VirusReverse Transcriptase InhibitorsVirus ReplicationZidovudineReceptors, CXCR4Receptors, VirusReverse Transcriptase InhibitorsZidovudine

Identifiers

PMID11333931
PMCPMC114955

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.