Evidence map›Paper›PMID 11331580›Full record

ArticleThe EMBO journal2001

The tripartite motif family identifies cell compartments.

A Reymond, G Meroni, A Fantozzi, G Merla, S Cairo, L Luzi, D Riganelli, E Zanaria, S Messali, S Cainarca and 4 more

Abstract read
In one paragraph

Article in The EMBO journal, 2001. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 719 papers.

0numbers the graph read from it
0cells of the map it votes in
719citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

719 citing papers in PubMed.

  1. Discovery of novel murine PML isoforms.Nucleus (Austin, Tex.) · 2026
    Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. TRIM21 is a molecular rheostat for influenza A virus replication.bioRxiv : the preprint server for biology · 2026
    Article
  14. Article
  15. Article
  16. Review
  17. TRIM family proteins: dual roles in tumor immunity.Frontiers in cell and developmental biology · 2026
    Review
  18. Novel Missense Variants inCardiology and cardiovascular medicine · 2026
    Article
  19. Article
  20. MacrophageAutophagy · 2025
    Article

659 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

A ReymondTelethon Institute of Genetics and Medicine (TIGEM), San Raffaele Biomedical Science Park, Milan, Italy.
G Meroni
A Fantozzi
G Merla
S Cairo
L Luzi
D Riganelli
E Zanaria
S Messali
S Cainarca
A Guffanti
S Minucci
P G Pelicci
A Ballabio

Funding

Telethon TGM06S01
6 · The paper itself

Abstract

A functional genomic approach, based on systematic data gathering, was used to characterize a family of proteins containing a tripartite motif (TRIM). A total of 37 TRIM genes/proteins were studied, 21 of which were novel. The results demonstrate that TRIM proteins share a common function: by means of homo-multimerization they identify specific cell compartments.

Indexed as

Carrier ProteinsNerve Tissue ProteinsAmino Acid MotifsAnimalsBlotting, NorthernCell CompartmentationCell LineChromosome MappingCloning, MolecularDatabases, FactualEmbryo, MammalianHumansIn Situ HybridizationMiceMolecular Sequence DataMultigene FamilyCarrier ProteinsNerve Tissue ProteinsProteinsTrim8 protein, mouseUbiquitin-Protein Ligases

Identifiers

PMID11331580
PMCPMC125245

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.