Evidence map›Paper›PMID 11326036›Full record

ArticleJournal of clinical microbiology2001

Evaluation of PCR using TRC(4) and IS6110 primers in detection of tuberculous meningitis.

S Narayanan, V Parandaman, P R Narayanan, P Venkatesan, C Girish, S Mahadevan, S Rajajee

Open access · greenAbstract readEvaluation Study
In one paragraph

Article in Journal of clinical microbiology, 2001. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 1 pooled it
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 1 synthesis or guideline pooled it, 66 citations in OpenAlex.

  1. Pooled it
  2. Review
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  12. Performance of a pyrosequencing platform in diagnosing drug-resistant extra-pulmonary tuberculosis in India.The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease · 2016
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  14. Occurrence of female genital tuberculosis among infertile women: a study from a tertiary maternal health care research centre in South India.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2014
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

S NarayananTuberculosis Research Centre, Mayor V.R. Ramanathan Road, Chetput, Chennai 600 031, India. Sujatha36@hotmail.com
V Parandaman
P R Narayanan
P Venkatesan
C Girish
S Mahadevan
S Rajajee
National Institute of Research in Tuberculosis · INJawaharlal Institute of Post Graduate Medical Education and Research · INKanchi Kamakoti CHILDS Trust Hospital · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We have evaluated a new set of primers (TRC(4)) in comparison with the IS6110 primers commonly used in PCR to detect tuberculous meningitis among children. The levels of concordance between the results of IS6110 PCR and TRC(4) PCR with cerebrospinal fluid specimens from patients with clinically confirmed tuberculous meningitis were 80 and 86%, respectively. Results with the two primer sets were concordant for 55 positive and 22 negative specimens (n = 98). We conclude that the sensitivity of PCR can be increased by using both IS6110 and TRC(4) primers.

Indexed as

Cerebrospinal FluidChildChild, PreschoolDNA, BacterialDNA PrimersDNA Transposable ElementsHumansMycobacterium tuberculosisPolymerase Chain ReactionRepetitive Sequences, Nucleic AcidSensitivity and SpecificityTuberculosis, MeningealDNA, BacterialDNA PrimersDNA Transposable Elements

Identifiers

PMID11326036
PMCPMC88071
OpenAlexW2046245826

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.