Evidence map›Paper›PMID 11326023›Full record

ArticleJournal of clinical microbiology2001

Real-time PCR assay targeting IS481 of Bordetella pertussis and molecular basis for detecting Bordetella holmesii.

U Reischl, N Lehn, G N Sanden, M J Loeffelholz

Abstract readEvaluation Study
In one paragraph

Article in Journal of clinical microbiology, 2001. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 58 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
58citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

58 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. SEVERE PERTUSSIS IN CHILDHOOD: UPDATE AND CONTROVERSY - SYSTEMATIC REVIEW.Revista paulista de pediatria : orgao oficial da Sociedade de Pediatria de Sao Paulo · 2019
    Pooled it
  2. Article
  3. Article
  4. Article
  5. AsymptomaticeLife · 2021
    Observational
  6. AsymptomaticmedRxiv : the preprint server for health sciences · 2020
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Evaluation of the AriesJournal of clinical microbiology · 2019
    Article
  12. Multicenter Clinical Evaluation of the Automated AriesJournal of clinical microbiology · 2019
    Article
  13. Article
  14. Comparing the Yield of Nasopharyngeal Swabs, Nasal Aspirates, and Induced Sputum for Detection of Bordetella pertussis in Hospitalized Infants.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2016
    Article
  15. Article
  16. Article
  17. Review
  18. Laboratory Diagnosis of Pertussis.Clinical microbiology reviews · 2015
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

U ReischlInstitute of Medical Microbiology and Hygiene, University of Regensburg, Franz-Josef-Strauss-Allee 11, D-93053 Regensburg, Germany. Udo.Reischl@klinik.uni-regensburg.de
N Lehn
G N Sanden
M J Loeffelholz

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Detection of Bordetella holmesii by a real-time PCR assay targeting IS481 of Bordetella pertussis is reported. Sequencing of IS481-specific PCR products from B. pertussis and B. holmesii isolates revealed sequence homology. Restriction fragment length polymorphism demonstrated a low copy number of IS481-like sequences in B. holmesii. These results, and culture of B. holmesii from patients with cough, suggest that the specificity and predictive value of IS481-based PCR assays for pertussis may be compromised.

Indexed as

BordetellaBordetella InfectionsBordetella pertussisDNA Transposable ElementsHumansMolecular Sequence DataPolymerase Chain ReactionPolymorphism, Restriction Fragment LengthSensitivity and SpecificityDNA Transposable Elements

Identifiers

PMID11326023
PMCPMC88058

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.