ArticlePostgraduate medical journal2001
Importance of family history in type 2 black South African diabetic patients.
Article in Postgraduate medical journal, 2001. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
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Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it, 59 citations in OpenAlex.
- Heritability and Genetics of Type 2 Diabetes Mellitus in Sub-Saharan Africa: A Systematic Review and Meta-Analysis.Journal of diabetes research · 2020Pooled it
- Prevalence and associated risk factors of Pseudomonas aeruginosa infection in Diabetic wounds in Duhok province, Iraq.PloS one · 2026Article
- Association of type 2 diabetes with family history of diabetes, diabetes biomarkers, mental and physical disorders in a Kenyan setting.Scientific reports · 2024Article
- Integration of point-of-care screening for type 2 diabetes mellitus and hypertension into the COVID-19 vaccine programme in Johannesburg, South Africa.BMC public health · 2023Article
- Self-Management of Diabetes and Associated Factors among Patients Seeking Chronic Care in Tshwane, South Africa: A Facility-Based Study.International journal of environmental research and public health · 2023Article
- Type 2 diabetes mellitus in sub-Saharan Africa: challenges and opportunities.Nature reviews. Endocrinology · 2022Review
- Factors associated with glycemic control among South African adult residents of Mkhondo municipality living with diabetes mellitus.Medicine · 2020Article
- Impact of Knowledge and Practice on Fasting Blood Glucose Levels among Diabetics During Ramadan Fasting.Journal of epidemiology and global health · 2019Article
- Performance of the Achutha Menon Centre Diabetes Risk Score in Identifying Prevalent Diabetes in Tamil Nadu, India.Diabetes & metabolism journal · 2017Article
- Presence of diabetes mellitus in the 'Dawoodi Bohra youth community' in Udaipur, Rajasthan.The Indian journal of medical research · 2014Article
- The potential impact of family history of metabolic syndrome and risk of type 2 diabetes mellitus: In a highly endogamous population.Indian journal of endocrinology and metabolism · 2014Article
- The surprising influence of family history to type 2 diabetes on anaerobic performance of young male élite athletes.SpringerPlus · 2014Article
- Familial Clustering of Type 2 Diabetes among Omanis.Oman medical journal · 2014Article
- The effect of perceived stress and family functioning on people with type 2 diabetes mellitus.Journal of clinical and diagnostic research : JCDR · 2013Article
- Parental transmission of type 2 diabetes mellitus in a highly endogamous population.World journal of diabetes · 2013Article
- Type 2 diabetes family histories, body composition and fasting glucose levels: a cross-section analysis in healthy sedentary male and female.Iranian journal of public health · 2013Article
- Developmental origins of type 2 diabetes in aboriginal youth in Canada: it is more than diet and exercise.Journal of nutrition and metabolism · 2012Article
- Maternal effect and familial aggregation in a type 2 diabetic Moroccan population.Journal of community health · 2011Article
- Association of comorbid depression, anxiety, and stress disorders with Type 2 diabetes in Bahrain, a country with a very high prevalence of Type 2 diabetes.Journal of endocrinological investigation · 2008Article
- Familial aggregation and excess maternal transmission of type 2 diabetes in Tunisia.Postgraduate medical journal · 2007Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo assess the family history of diabetes in type 2 black South African diabetics with emphasis on the parental phenotype.
designProspective case-control study in which family histories were obtained from patients.
settingDiabetic clinic of a provincial teaching hospital in the Transkei region of South Africa. SUBJECTS: A total of 1111 type 2 diabetics attending the diabetic clinic and 687 controls.
main outcome measuresHistory of diabetes in parents, siblings, maternal and paternal grandparents, aunts, and uncles.
resultsAltogether 27.3% of diabetic subjects had a family history of diabetes compared with 8.4% in the control group (p<0.01). Among the group with positive family history 82.6% reported only one diabetic family member, while 17.4% reported at least two relatives; 6.6% had a diabetic relative from both maternal and paternal sides, and 87.8% had first degree relative with diabetes. Among them there was a significant maternal aggregation with 64.7% of patients having a diabetic mother compared with 27% who had a diabetic father (p<0.01). No maternal effect was observed among the second and third degree relatives. Patients with positive family history had an earlier onset of diabetes than those without family history (p<0.01).
conclusionThese data suggest that type 2 diabetes is heritable in black South African diabetics. It is also likely that maternal influences may play an important part.
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