How activated receptors couple to G proteins.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

66 citing papers in PubMed.

1. Pathophysiological significance and modulation of the transient receptor potential canonical 3 ion channel.Medicinal research reviews · 2024
   Review
2. Deciphering the role of glycosaminoglycans in GPCR signaling.Cellular signalling · 2024
   Review
3. Gonadotropin-Releasing Hormone Receptor (GnRHR) and Hypogonadotropic Hypogonadism.International journal of molecular sciences · 2023
   Review
4. Molecular Mechanisms of PTH/PTHrP Class B GPCR Signaling and Pharmacological Implications.Endocrine reviews · 2023
   Article
5. Genetically encoded tools for in vivo G-protein-coupled receptor agonist detection at cellular resolution.Clinical and translational medicine · 2022
   Review
6. Emerging approaches for decoding neuropeptide transmission.Trends in neurosciences · 2022
   Review
7. Trypsin-Like Proteases and Their Role in Muco-Obstructive Lung Diseases.International journal of molecular sciences · 2021
   Review
8. A Dynamic, Split-Luciferase-Based Mini-G Protein Sensor to Functionally Characterize Ligands at All Four Histamine Receptor Subtypes.International journal of molecular sciences · 2020
   Article
9. Valsartan impedes epinephrine-induced ICAM-4 activation on normal, sickle cell trait and sickle cell disease red blood cells.PloS one · 2019
   Article
10. Cryo-EM structure of human rhodopsin bound to an inhibitory G protein.Nature · 2018
    Article
11. Discovery of novel frizzled-7 inhibitors by targeting the receptor's transmembrane domain.Oncotarget · 2017
    Article
12. Label-Free Imaging of Histamine Mediated G Protein-Coupled Receptors Activation in Live Cells.Analytical chemistry · 2016
    Article
13. Evolution of the protease-activated receptor family in vertebrates.International journal of molecular medicine · 2016
    Article
14. Opposite effects of KCTD subunit domains on GABA(B) receptor-mediated desensitization.The Journal of biological chemistry · 2012
    Article
15. Frizzled7 as an emerging target for cancer therapy.Cellular signalling · 2012
    Review
16. Disrupting microtubule network immobilizes amoeboid chemotactic receptor in the plasma membrane.Biochimica et biophysica acta · 2011
    Article
17. G protein activation by serotonin type 4 receptor dimers: evidence that turning on two protomers is more efficient.The Journal of biological chemistry · 2011
    Article
18. Activation state of the M3 muscarinic acetylcholine receptor modulates mammalian odorant receptor signaling.Science signaling · 2011
    Article
19. Molecular organization and dynamics of the melatonin MT₁ receptor/RGS20/G(i) protein complex reveal asymmetry of receptor dimers for RGS and G(i) coupling.The EMBO journal · 2010
    Article
20. Activators of G-protein signaling 3: a drug addiction molecular gateway.Behavioural pharmacology · 2010
    Review

6 more citing papers are in PubMed but not listed here.

Corrections and comments

• Comment on
  Structure and function in rhodopsin: Mass spectrometric identification of the abnormal intradiscal disulfide bond in misfolded retinitis pigmentosa mutants.2001
• Comment on
  Mapping of contact sites in complex formation between transducin and light-activated rhodopsin by covalent crosslinking: use of a photoactivatable reagent.2001
• Comment on
  Mapping of contact sites in complex formation between light-activated rhodopsin and transducin by covalent crosslinking: use of a chemically preactivated reagent.2001
• Comment on
  Solution 19F nuclear Overhauser effects in structural studies of the cytoplasmic domain of mammalian rhodopsin.2001

Authors and funding

1 author.

Funding

No grant is acknowledged in the PubMed record.

Abstract

PubMed holds no abstract for this paper.

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