ArticleProceedings of the National Academy of Sciences of the United States of America2001
BRS1, a serine carboxypeptidase, regulates BRI1 signaling in Arabidopsis thaliana.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2001. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 96 papers, 1 of them a synthesis that pooled it.
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Who cites it
96 citing papers in PubMed, 1 synthesis or guideline pooled it, 236 citations in OpenAlex.
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- Proteomics revealed novel functions and drought tolerance of Arabidopsis thaliana protein kinase ATG1.BMC biology · 2025Article
- Phylogenomic and synteny analysis of BAHD and SCP/SCPL gene families reveal their evolutionary histories in plant specialized metabolism.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2024Article
- Brassinosteroid biosynthesis and signaling: Conserved and diversified functions of core genes across multiple plant species.Plant communications · 2024Review
- Molecular Lesions in BRI1 and Its Orthologs in the Plant Kingdom.International journal of molecular sciences · 2024Review
- Genome-Wide Analysis ofInternational journal of molecular sciences · 2024Article
- ERF49 mediates brassinosteroid regulation of heat stress tolerance in Arabidopsis thaliana.BMC biology · 2022Article
- Receptor-like Kinases (LRR-RLKs) in Response of Plants to Biotic and Abiotic Stresses.Plants (Basel, Switzerland) · 2022Review
- Modulation of receptor-like transmembrane kinase 1 nuclear localization by DA1 peptidases in Arabidopsis.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
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- Identification of Candidate Genes for Lint Percentage and Fiber Quality Through QTL Mapping and Transcriptome Analysis in an Allotetraploid Interspecific Cotton CSSLs Population.Frontiers in plant science · 2022Article
- Plant protease as regulator and signaling molecule for enhancing environmental stress-tolerance.Plant cell reports · 2021Review
- Genome-wide expression and network analyses of mutants in key brassinosteroid signaling genes.BMC genomics · 2021Article
- BRS1 mediates plant redox regulation and cold responses.BMC plant biology · 2021Article
- Genome-wide analysis of the serine carboxypeptidase-like protein family in Triticum aestivum reveals TaSCPL184-6D is involved in abiotic stress response.BMC genomics · 2021Article
- High quality genome of Erigeron breviscapus provides a reference for herbal plants in Asteraceae.Molecular ecology resources · 2021Article
36 more citing papers are in PubMed but not listed here.
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4 authors at 2 institutions in 1 country.
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Abstract
Brassinosteroid-insensitive 1 (BRI1) of Arabidopsis thaliana encodes a cell surface receptor for brassinosteroids. Mutations in BRI1 severely affect plant growth and development. Activation tagging of a weak bri1 allele (bri1-5) resulted in the identification of a new locus, brs1-1D. BRS1 is predicted to encode a secreted carboxypeptidase. Whereas a brs1 loss-of-function allele has no obvious mutant phenotype, overexpression of BRS1 can suppress bri1 extracellular domain mutants. Genetic analyses showed that brassinosteroids and a functional BRI1 protein kinase domain are required for suppression. In addition, overexpressed BRS1 missense mutants, predicted to abolish BRS1 protease activity, failed to suppress bri1-5. Finally, the effects of BRS1 are selective: overexpression in either wild-type or two other receptor kinase mutants resulted in no phenotypic alterations. These results strongly suggest that BRS1 processes a protein involved in an early event in the BRI1 signaling.
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