ArticleDigestive diseases and sciences2001
Apoptosis induced by ischemia-reperfusion and fasting in gastric mucosa compared to small intestinal mucosa in rats.
Article in Digestive diseases and sciences, 2001. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 46 citations in OpenAlex.
- Use of sildenafil and L-arginine in an experimental rat model for the prevention of neonatal necrotizing enterocolitis.Scientific reports · 2022Article
- Muscular tissue oxygen saturation during robotic hysterectomy and postoperative nausea and vomiting: exploring the potential therapeutic thresholds.Journal of clinical monitoring and computing · 2019Observational
- Remifentanil ameliorates intestinal ischemia-reperfusion injury.BMC gastroenterology · 2013Article
- Intestinal mucosal atrophy and adaptation.World journal of gastroenterology · 2012Review
- The role of curcumin on intestinal oxidative stress, cell proliferation and apoptosis after ischemia/reperfusion injury in rats.Journal of molecular histology · 2011Article
- Mitochondrial dependent apoptosis: ameliorative effect of flunarizine on ischemia-reperfusion of celiac artery-induced gastric lesions in the rat.Digestive diseases and sciences · 2011Article
- Protective effect and mechanisms of radix astragali injection on the intestinal mucosa of rats with obstructive jaundice.Mediators of inflammation · 2010Article
- Mechanism of acute pancreatitis complicated with injury of intestinal mucosa barrier.Journal of Zhejiang University. Science. B · 2007Review
- Effects of hypothalamic paraventricular nuclei on apoptosis and proliferation of gastric mucosal cells induced by ischemia/reperfusion in rats.World journal of gastroenterology · 2007Article
- Extracellular signal-regulated kinase 1- and 2-mediated gastric mucosal injury and repair in gastric ischemia-reperfusion of rats.Journal of gastroenterology · 2006Article
- Intestinal apoptotic changes linked to metabolic status in fasted and refed rats.Pflugers Archiv : European journal of physiology · 2006Article
- Oral arginine improves intestinal recovery following ischemia-reperfusion injury in rat.Pediatric surgery international · 2005Article
- Effects of intestinal lymph on expression of neutrophil adhesion factors and lung injury after trauma-induced shock.World journal of gastroenterology · 2004Article
- Early protective effect of ischemic preconditioning on small intestinal graft in rats.World journal of gastroenterology · 2003Article
- Reciprocal variations of nNOS and HSP90 are associated with fasting in gastrointestinal tract of the piglet.Digestive diseases and sciences · 2003Article
- The role of the intestine in the pathophysiology and management of severe acute pancreatitis.HPB : the official journal of the International Hepato Pancreato Biliary Association · 2003Article
- Role of changes in tissular nucleotides on the development of apoptosis during ischemia/reperfusion in rat small bowel.The American journal of pathology · 2002Article
- THE PROTECTIVE ROLE OF ESTRADIOL & PROGESTERONE IN MALE RATS, FOLLOWING GASTRIC ISCHEMIA-REPERFUSION.Acta endocrinologica (Bucharest, Romania : 2005)Article
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Authors and funding
9 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The effect of ischemia-reperfusion and 48-hr fasting on apoptosis was characterized in rat gastric mucosa and compared to small intestinal mucosa. Under halothane anesthesia, the celiac artery or superior mesenteric artery in the rat was occluded for 60 min followed by reperfusion. Occlusion of the celiac artery reduced blood flow in the stomach and occlusion of the mesenteric artery reduced blood flow in the small intestine. Additional rats were fasted for 48 hr to evaluate the effect of fasting on mucosal apoptosis. The ratios of fragmented DNA to total DNA, electrophoresis, and immunohistochemical staining were examined after ischemia-reperfusion or fasting. Apoptosis was not induced significantly in the gastric mucosa after ischemia-reperfusion, although it increased dramatically in the intestinal mucosa after ischemia-reperfusion. Further, after 48 fasting, apoptosis was induced in the small intestine, but not in the stomach. These results indicate that rat gastric mucosa is not as sensitive as small intestinal mucosa to ischemia-reperfusion or fasting-induced apoptosis.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.