ReviewThe Biochemical journal2001
Electrospray and tandem mass spectrometry in biochemistry.
Review in The Biochemical journal, 2001. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed.
- Mass shift in mass spectrometry imaging: comprehensive analysis and practical corrective workflow.Analytical and bioanalytical chemistry · 2021Article
- Laboratory Diagnosis of Lysosomal Diseases: Newborn Screening to Treatment.The Clinical biochemist. Reviews · 2020Review
- Interfacing low-energy SAW nebulization with Liquid Chromatography-Mass Spectrometry for the analysis of biological samples.Scientific reports · 2015Article
- The Role of Mass Spectrometry in the "Omics" Era.Current organic chemistry · 2013Article
- Antibody screening identifies 78 putative host proteins involved in Cyprinid herpesvirus 3 infection or propagation in common carp, Cyprinus carpio L.Journal of fish diseases · 2013Article
- Lipidomics of oxidized polyunsaturated fatty acids.Free radical biology & medicine · 2013Article
- Sub-cellular proteomics of Medicago truncatula.Frontiers in plant science · 2013Article
- Retrobiosynthetic approach delineates the biosynthetic pathway and the structure of the acyl chain of mycobacterial glycopeptidolipids.The Journal of biological chemistry · 2012Article
- Electrospray ionization mass spectrometry: a technique to access the information beyond the molecular weight of the analyte.International journal of analytical chemistry · 2012Article
- Evidence of molecular fragmentation inside the charged droplets produced by electrospray process.Journal of the American Society for Mass Spectrometry · 2011Article
- Measurement of steroid concentrations in brain tissue: methodological considerations.Frontiers in endocrinology · 2011Article
- A statistically rigorous test for the identification of parent-fragment pairs in LC-MS datasets.Analytical chemistry · 2010Article
- Proteomics-based investigation in C2C12 myoblast differentiation.European journal of histochemistry : EJH · 2009Article
- Sequence Analysis of Native Oligosaccharides Using Negative ESI Tandem MS.Current analytical chemistry · 2009Article
- Analysis of protein posttranslational modifications by mass spectrometry: With special reference to haemoglobin.Indian journal of clinical biochemistry : IJCB · 2009Article
- Microbial proteomics: a mass spectrometry primer for biologists.Microbial cell factories · 2007Article
- Investigation of the metabolism of substance P at the blood-brain barrier using LC-MS/MS.Journal of pharmaceutical and biomedical analysis · 2007Article
- Human autoantibodies to diacyl-phosphatidylethanolamine recognize a specific set of discrete cytoplasmic domains.Clinical and experimental immunology · 2006Article
- Application of electrospray ionization mass spectrometry to study the hydrophobic interaction between the epsilon and theta subunits of DNA polymerase III.Protein science : a publication of the Protein Society · 2004Article
- Proteomics for protein expression profiling in neuroscience.Neurochemical research · 2004Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Over the last 20 years, biological MS has changed out of all recognition. This is primarily due to the development in the 1980s of 'soft ionization' methods that permit the ionization and vaporization of large, polar, and thermally labile biomolecules. These developments in ionization mode have driven the design and manufacture of smaller and cheaper mass analysers, making the mass spectrometer a routine instrument in the biochemistry laboratory today. In the present review the revolutionary 'soft ionization' methods will be discussed with particular reference to electrospray. The mass analysis of ions will be described, and the concept of tandem MS introduced. Where appropriate, examples of the application of MS in biochemistry will be provided. Although the present review will concentrate on the MS of peptides/proteins and lipids, all classes of biomolecules can be analysed, and much excellent work has been done in the fields of carbohydrate and nucleic acid biochemistry.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.