ReviewGenome biology2001
Dystrophins and dystrobrevins.
Review in Genome biology, 2001. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
17 citing papers in PubMed.
- Enhanced therapeutic potential of a microdystrophin with an extended C-terminal domain.Molecular therapy. Methods & clinical development · 2025Article
- Characterizing genetic variation on the Z chromosome in Schistosoma japonicum reveals host-parasite co-evolution.Parasites & vectors · 2024Article
- RotaRod and acoustic startle reflex performance of two potential mouse models for Meniere's disease.The European journal of neuroscience · 2023Article
- A new immunodeficient Duchenne muscular dystrophy rat model to evaluate engraftment after human cell transplantation.Frontiers in physiology · 2023Article
- Review
- Transplantation of human iPSC-derived muscle stem cells in the diaphragm of Duchenne muscular dystrophy model mice.PloS one · 2022Article
- Dp412e: a novel human embryonic dystrophin isoform induced by BMP4 in early differentiated cells.Skeletal muscle · 2015Article
- Article
- Thermodynamic stability, unfolding kinetics, and aggregation of the N-terminal actin-binding domains of utrophin and dystrophin.Proteins · 2012Article
- α-Dystrobrevin distribution and association with other proteins in human promyelocytic NB4 cells treated for granulocytic differentiation.Molecular biology reports · 2011Article
- Missense mutations in dystrophin that trigger muscular dystrophy decrease protein stability and lead to cross-beta aggregates.Proceedings of the National Academy of Sciences of the United States of America · 2010Article
- The dystrotelin, dystrophin and dystrobrevin superfamily: new paralogues and old isoforms.BMC genomics · 2007Article
- Glutamate regulates dystrophin-71 levels in glia cells.Neurochemical research · 2005Article
- Association of alpha-dystrobrevin with reorganizing tight junctions.The Journal of membrane biology · 2005Article
- Characterization of human alpha-dystrobrevin isoforms in HL-60 human promyelocytic leukemia cells undergoing granulocytic differentiation.Molecular biology of the cell · 2002Article
- Genetic variation in the 6p22.3 gene DTNBP1, the human ortholog of the mouse dysbindin gene, is associated with schizophrenia.American journal of human genetics · 2002Article
- Diversity of the Brain Dystrophin-Glycoprotein Complex.Journal of biomedicine & biotechnology · 2002Article
Corrections and comments
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Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
summaryA unique arrangement of domains makes up the common region of two otherwise very different proteins - long, elegant dystrophin, and its rather dumpy distant cousin, dystrobrevin. The two work in concert, forming the core of a large membrane-bound complex in all metazoa. Like many proteins, dystrophin and dystrobrevin have diversified in the vertebrate clade, as have their binding partners, yielding specialized complexes tailored to different cellular and subcellular locations. Disruption of several components of the complex is known to result in syndromes that include progressive myopathy, sometimes combined with cognitive defects; the best known of these is Duchenne muscular dystrophy. Despite a wealth of biochemical, cell biological and genetic information, the precise role of dystrophins, dystrobrevins and their collaborators remains unclear.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.