ArticleJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology
Prognostic value of dipyridamole SPECT imaging in low-risk patients after myocardial infarction.
Article in Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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9 citing papers in PubMed, 23 citations in OpenAlex.
- Prognostic value of stress Tc-99m tetrofosmin SPECT in patients with previous myocardial infarction: impact of scintigraphic extent of coronary artery disease.Journal of nuclear cardiology : official publication of the American Society of Nuclear CardiologyTrial
- Adenosine sestamibi SPECT post-infarction evaluation (INSPIRE) trial: A randomized, prospective multicenter trial evaluating the role of adenosine Tc-99m sestamibi SPECT for assessing risk and therapeutic outcomes in survivors of acute myocardial infarction.Journal of nuclear cardiology : official publication of the American Society of Nuclear CardiologyTrial
- Article
- In-hospital complications in acute ST-elevation myocardial infarction depending on renal function.Herzschrittmachertherapie & Elektrophysiologie · 2021Observational
- Risk stratification with vasodilator stress SPECT myocardial perfusion imaging in patients with elevated cardiac biomarkers.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2020Article
- The troponin conundrum: clarification through stress myocardial perfusion SPECT.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2007Article
- Depressed heart rate response to vasodilator stress for myocardial SPECT predicts mortality in patients after myocardial infarction.The international journal of cardiovascular imaging · 2006Article
- Role of nuclear cardiac imaging in myocardial infarction: postinfarction risk stratification.Journal of nuclear cardiology : official publication of the American Society of Nuclear CardiologyReview
- Myocardial metabolic imaging in the acute care setting.Journal of nuclear cardiology : official publication of the American Society of Nuclear CardiologyReview
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5 authors at 3 institutions in 2 countries.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundThe prognostic value of perfusion imaging was assessed in low-risk patients after myocardial infarction (MI) and compared with clinical and angiographic variables. METHODS AND
resultsRest thallium and dipyridamole technetium 99m sestamibi single photon emission computed tomography imaging was performed in 203 (91%) low-risk patients 3 to 21 days after MI who were enrolled in a trial of low-dose warfarin sodium and aspirin. Patients were considered low risk with planned nonintervention, on the basis of an uncomplicated course after MI, negative submaximal stress electrocardiography, and the absence of significant angiographic disease requiring revascularization. During a minimum follow-up of 12 months, 69 patients (34%) had clinical events: 1 cardiac death, 7 MIs, 26 admissions for unstable angina, 18 coronary bypass grafting, and 17 angioplasty. Univariate analysis identified the extent of significant angiographic stenoses (> or =70%) and the extent of scintigraphic defect as predictive of future events. On multivariate analysis, the presence of any scintigraphic reversibility had the strongest correlation with clinical events, with better predictive value than angiographic multivessel stenoses (P =.0006 vs P =.003).
conclusionsIn the low-risk population after MI, scintigraphic reversibility remains a strong predictor of cardiac events, with greater prognostic value than angiographic data. The extent of scintigraphic reversibility was directly correlated with clinical events. Therefore scintigraphic imaging remains clinically relevant for risk stratification in the current low-risk population after MI.
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