ArticleJournal of assisted reproduction and genetics2001
Soluble CD44 in human ovarian follicular fluid.
Article in Journal of assisted reproduction and genetics, 2001. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
5 citing papers in PubMed, 22 citations in OpenAlex.
- Effect of D-Glucuronic Acid and N-acetyl-D-Glucosamine Treatment during In Vitro Maturation on Embryonic Development after Parthenogenesis and Somatic Cell Nuclear Transfer in Pigs.Animals : an open access journal from MDPI · 2021Article
- Article
- MiRNA-320 in the human follicular fluid is associated with embryo quality in vivo and affects mouse embryonic development in vitro.Scientific reports · 2015Article
- Follicular proinflammatory cytokines and chemokines as markers of IVF success.Clinical & developmental immunology · 2012Article
- Follicular fluid content and oocyte quality: from single biochemical markers to metabolomics.Reproductive biology and endocrinology : RB&E · 2009Review
Corrections and comments
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeIn the present study, we investigated the existence of soluble CD44 (sCD44) in human follicular fluid, the relationship between the concentration of sCD44 and that of other hormonal parameters, and the prognostic value of sCD44 in follicular fluid in in vitro fertilization (IVF) programs.
methodsA total of 63 follicular fluid specimens from patients (n = 30) participating in our IVF programs was analyzed by RIA and enzyme-linked immunosorbent assay (ELISA).
resultsThe mean concentration (+/- SE) of sCD44 in follicular fluid was 265.4 +/- 7.8 ng/ml. The variation of the follicular fluid concentration of sCD44 was strictly associated with that of human chorionic gonadotropin (hCG) (r = 0.572, P < 0.0001). The mean concentration of sCD44 in follicular fluid was significantly higher in follicles containing subsequently unfertilized oocytes than that in those containing oocytes that had undergone fertilization (P = 0.0428). In the analysis of each follicle that contained an oocyte subsequently fertilized, the mean concentration of sCD44 was significantly higher in follicular fluid with the subsequently good-quality embryos than in that with the subsequently poor-quality embryos (P < 0.05).
conclusionsThese results indicated that the concentration of sCD44 in follicular fluid reflects the development of embryos derived from the same follicle, so the sCD44 in human follicular fluid may be useful in the assessment of the prognostic value of IVF programs.
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