Evidence map›Paper›PMID 11292820›Full record

ArticleJournal of bacteriology2001

Growth phase variation in cell and nucleoid morphology in a Bacillus subtilis recA mutant.

S A Sciochetti, G W Blakely, P J Piggot

Open access · greenAbstract readComparative Study
In one paragraph

Article in Journal of bacteriology, 2001. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
0.7field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 31 citations in OpenAlex.

  1. Article
  2. Microbiology and molecular biology reviews : MMBR · 2024
    Review
  3. Review
  4. Article
  5. Generation of Markerless Deletions in the Nosocomial PathogenApplied and environmental microbiology · 2019
    Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

S A SciochettiDepartment of Microbiology and Immunology, Temple University School of Medicine, Philadelphia, Pennsylvania 19140, USA.
G W Blakely
P J Piggot
Temple University · USUniversity of Edinburgh · GB

Funding

GENE EXPRESSION DURING SPORULATIONR01GM043577 · NIGMS · TEMPLE UNIV OF THE COMMONWEALTH · PI PIGGOT, PATRICK J. · 1990 to 2012
$3.9M
TRAINING PROGRAMS IN MICROBIOLOGY &IMMUNOLOGYT32AI007101 · NIAID · TEMPLE UNIV OF THE COMMONWEALTH · PI GANEA, DOINA · 1985 to 2008
$2.4M
NIAID NIH HHS T32 AI007101NIAID NIH HHS T32 AI-07101NIGMS NIH HHS GM-43577NIGMS NIH HHS R01 GM043577
6 · The paper itself

Abstract

The major role of RecA is thought to be in helping repair and restart stalled replication forks. During exponential growth, Bacillus subtilis recA cells exhibited few microscopically observable nucleoid defects. However, the efficiency of plating was about 12% of that of the parent strain. A substantial and additive defect in viability was also seen for addB and recF mutants, suggesting a role for the corresponding recombination paths during normal growth. Upon entry into stationary phase, a subpopulation (approximately 15%) of abnormally long cells and nucleoids developed in B. subtilis recA mutants. In addition, recA mutants showed a delay in, and a diminished capacity for, effecting prespore nucleoid condensation.

Indexed as

ExodeoxyribonucleasesBacillus subtilisBacterial ProteinsCell NucleusColony Count, MicrobialDNA-Binding ProteinsFluorescent DyesIndolesMutationRec A RecombinasesSpores, BacterialAddB protein, Bacillus subtilisBacterial ProteinsDAPIDNA-Binding ProteinsExodeoxyribonucleasesFluorescent DyesIndolesRec A RecombinasesrecF protein, Bacteria

Identifiers

PMID11292820
PMCPMC99517
OpenAlexW2022559772

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.