ReviewClinical microbiology reviews2001
Leptospirosis.
Review in Clinical microbiology reviews, 2001. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1,157 papers, 8 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1,157 citing papers in PubMed, 8 syntheses or guidelines pooled it, 2,315 citations in OpenAlex.
- Leptospirosis and its co-infections in India: prevalence, geographic distribution, and clinical implications.BMC infectious diseases · 2026Pooled it
- Corticosteroids for treatment of leptospirosis.The Cochrane database of systematic reviews · 2025Pooled it
- Zoonotic pathogens in equids in Central Europe: a systematic review.BMC veterinary research · 2025Pooled it
- Epidemiology of human and animal leptospirosis in Kenya: A systematic review and meta-analysis of disease occurrence, serogroup diversity and risk factors.PLoS neglected tropical diseases · 2024Pooled it
- Efficacy and safety of antibiotics for treatment of leptospirosis: a systematic review and network meta-analysis.Systematic reviews · 2024Pooled it
- Antibiotics for treatment of leptospirosis.The Cochrane database of systematic reviews · 2024Pooled it
- Antibiotic prophylaxis for leptospirosis.The Cochrane database of systematic reviews · 2024Pooled it
- Diagnosis of human leptospirosis: systematic review and meta-analysis of the diagnostic accuracy of the Leptospira microscopic agglutination test, PCR targeting Lfb1, and IgM ELISA to Leptospira fainei serovar Hurstbridge.BMC infectious diseases · 2024Pooled it
- A systematic review ofOne health (Amsterdam, Netherlands) · 2026Article
- Novel Target for Pathogenic Leptospira Detection via Colorimetric Loop-Mediated Isothermal Amplification (LAMP): Development, Validation, and Comparative Analysis.Journal of clinical laboratory analysis · 2026Article
- Clinical features and outcomes of neuroleptospirosis in French Guiana: Insights from a retrospective study (2015-2021).PLoS neglected tropical diseases · 2026Article
- Wildlife Trade and Genetic Basis of Disease Susceptibility: A Review.International journal of immunogenetics · 2026Review
- Non-Oliguric IRIS Grade V Acute Kidney Injury Associated with Suspected Leptospirosis in an Urban Dog Unvaccinated Against Leptospirosis from the Republic of Korea: A Case Report.Veterinary sciences · 2026Article
- β-Lactam antibiotics trigger mouse TLR2/4- and human TLR2/5-dependent Jarisch-Herxheimer reaction in leptospirosis.bioRxiv : the preprint server for biology · 2026Article
- Integrated diagnostic approach for Leptospira spp. detection in SMEDI associated reproductive disease of swine.Veterinary and animal science · 2026Article
- The Epidemiological Scenario of Human Leptospirosis in Brazil from 2015 to 2024.Epidemiologia (Basel, Switzerland) · 2026Article
- First report of seropositivity to pathogenic Leptospira in backyard hens: potential poultry health issue and zoonotic risk.Poultry science · 2026Article
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- Application of FT-IR spectroscopy using the IR BiotyperEuropean journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2026Article
1,097 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Leptospirosis is a worldwide zoonotic infection with a much greater incidence in tropical regions and has now been identified as one of the emerging infectious diseases. The epidemiology of leptospirosis has been modified by changes in animal husbandry, climate, and human behavior. Resurgent interest in leptospirosis has resulted from large outbreaks that have received significant publicity. The development of simpler, rapid assays for diagnosis has been based largely on the recognition that early initiation of antibiotic therapy is important in acute disease but also on the need for assays which can be used more widely. In this review, the complex taxonomy of leptospires, previously based on serology and recently modified by a genotypic classification, is discussed, and the clinical and epidemiological value of molecular diagnosis and typing is also evaluated.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.