Evidence map›Paper›PMID 11287588›Full record

ArticleJournal of virology2001

In vivo accumulation of cyclin A and cellular replication factors in autonomous parvovirus minute virus of mice-associated replication bodies.

T Bashir, J Rommelaere, C Cziepluch

Abstract read
In one paragraph

Article in Journal of virology, 2001. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers.

0numbers the graph read from it
0cells of the map it votes in
51citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

51 citing papers in PubMed, 79 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

T BashirApplied Tumor Virology Unit F0100 and Institut National de la Santé et de la Recherche Médicale U 375, Deutsches Krebsforschungszentrum, D-69120 Heidelberg, Germany.
J Rommelaere
C Cziepluch
DKFZ-ZMBH Alliance · DEGerman Cancer Research Center · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Autonomous parvovirus minute virus of mice (MVM) DNA replication is strictly dependent on cellular factors expressed during the S phase of the cell cycle. Here we report that MVM DNA replication proceeds in specific nuclear structures termed autonomous parvovirus-associated replication bodies, where components of the basic cellular replication machinery accumulate. The presence of DNA polymerases alpha and delta in these bodies suggests that MVM utilizes partially preformed cellular replication complexes for its replication. The recruitment of cyclin A points to a role for this cell cycle factor in MVM DNA replication beyond its involvement in activating the conversion of virion single-stranded DNA to the duplex replicative form.

Indexed as

CDC2-CDC28 KinasesDNA ReplicationVirus ReplicationAnimalsCell NucleusCyclin ACyclin-Dependent Kinase 2Cyclin-Dependent KinasesDNA-Binding ProteinsDNA Polymerase IDNA Polymerase IIIHumansMiceMinute Virus of MiceProliferating Cell Nuclear AntigenProtein Serine-Threonine KinasesCDC2-CDC28 KinasesCDK2 protein, humanCdk2 protein, mouseCyclin ACyclin-Dependent Kinase 2Cyclin-Dependent KinasesDNA-Binding ProteinsDNA Polymerase IDNA Polymerase IIINS1 protein, minute virus of miceProliferating Cell Nuclear AntigenProtein Serine-Threonine KinasesReplication Protein ARPA1 protein, humanRpa1 protein, mouseViral Nonstructural Proteins

Identifiers

PMID11287588
PMCPMC114184
OpenAlexW2077223387

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.