ArticleApplied and environmental microbiology2001
Regulation of fumonisin B(1) biosynthesis and conidiation in Fusarium verticillioides by a cyclin-like (C-type) gene, FCC1.
Article in Applied and environmental microbiology, 2001. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
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33 citing papers in PubMed, 125 citations in OpenAlex.
- Rapid filamentous fungi gene knockout identification through high-throughput droplet microfluidics.Analytica chimica acta · 2025Article
- FvKex2 is required for development, virulence, and mycotoxin production in Fusarium verticillioides.Applied microbiology and biotechnology · 2024Article
- A putative terpene cyclase gene (Frontiers in microbiology · 2023Article
- The autophagy-related proteins FvAtg4 and FvAtg8 are involved in virulence and fumonisin biosynthesis inVirulence · 2022Article
- Cocultivation of Anaerobic Fungi with Rumen Bacteria Establishes an Antagonistic Relationship.mBio · 2021Article
- Advances in linking polyketides and non-ribosomal peptides to their biosynthetic gene clusters in Fusarium.Current genetics · 2019Review
- Genetic Differentiation Associated with Fumonisin and Gibberellin Production in JapaneseApplied and environmental microbiology · 2019Article
- The FlbA-regulated predicted transcription factor Fum21 of Aspergillus niger is involved in fumonisin production.Antonie van Leeuwenhoek · 2018Article
- The novel fungal-specific gene FUG1 has a role in pathogenicity and fumonisin biosynthesis in Fusarium verticillioides.Molecular plant pathology · 2017Article
- Article
- Multi-Homologous Recombination-Based Gene Manipulation in the Rice Pathogen Fusarium fujikuroi.The plant pathology journal · 2016Article
- Genetic Variability and Geographical Distribution of Mycotoxigenic Fusarium verticillioides Strains Isolated from Maize Fields in Texas.The plant pathology journal · 2015Article
- Transcriptome changes in Fusarium verticillioides caused by mutation in the transporter-like gene FST1.BMC microbiology · 2015Article
- Effect of fungicide on Fusarium verticillioides mycelial morphology and fumonisin B₁ production.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2015Article
- PFP1, a gene encoding an Epc-N domain-containing protein, is essential for pathogenicity of the barley pathogen Rhynchosporium commune.Eukaryotic cell · 2014Article
- Article
- Protein phosphatase 2A regulatory subunits perform distinct functional roles in the maize pathogen Fusarium verticillioides.Molecular plant pathology · 2013Article
- Conserved versatile master regulators in signalling pathways in response to stress in plants.AoB PLANTS · 2013Review
- Article
- Quantification of fungal colonization, sporogenesis, and production of mycotoxins using kernel bioassays.Journal of visualized experiments : JoVE · 2012Article
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Fumonisins are a group of mycotoxins produced in corn kernels by the plant-pathogenic fungus Fusarium verticillioides. A mutant of the fungus, FT536, carrying a disrupted gene named FCC1 (for Fusarium cyclin C1) resulting in altered fumonisin B(1) biosynthesis was generated. FCC1 contains an open reading frame of 1,018 bp, with one intron, and encodes a putative 319-amino-acid polypeptide. This protein is similar to UME3 (also called SRB11 or SSN8), a cyclin C of Saccharomyces cerevisiae, and contains three conserved motifs: a cyclin box, a PEST-rich region, and a destruction box. Also similar to the case for C-type cyclins, FCC1 was constitutively expressed during growth. When strain FT536 was grown on corn kernels or on defined minimal medium at pH 6, conidiation was reduced and FUM5, the polyketide synthase gene involved in fumonisin B(1) biosynthesis, was not expressed. However, when the mutant was grown on a defined minimal medium at pH 3, conidiation was restored, and the blocks in expression of FUM5 and fumonisin B(1) production were suppressed. Our data suggest that FCC1 plays an important role in signal transduction regulating secondary metabolism (fumonisin biosynthesis) and fungal development (conidiation) in F. verticillioides.
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