American College of Medical Genetics consensus statement on factor V Leiden mutation testing.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

36 citing papers in PubMed.

1. Association of factor V leiden and ischemic stroke in young adults: a national inpatient sample analysis.Journal of thrombosis and thrombolysis · 2026
   Article
2. Psychotic Disorder Secondary to Cerebral Venous Thrombosis Caused by Primary Thrombophilia in a Pediatric Patient with Protein S Deficiency and an MTHFR p.Ala222Val Variant: A Case Report.Hematology reports · 2025
   Article
3. Inherited thrombophilia transpires with severe coronary arterial thrombosis in wide range of age backgrounds: A report of 3 cases.Annals of medicine and surgery (2012) · 2022
   Article
4. Thrombophilic alterations, migraine, and vascular disease: results from a case-control study.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2021
   Article
5. The prevalence of Factor V Leiden (Arg506Gln) mutation in King Khalid University Hospital patients, 2017-2019.Nagoya journal of medical science · 2021
   Article
6. Direct-to-consumer genetic testing for factor V Leiden and prothrombin 20210G>A: the consumer experience.Molecular genetics & genomic medicine · 2020
   Article
7. A curated gene list for reporting results of newborn genomic sequencing.Genetics in medicine : official journal of the American College of Medical Genetics · 2017
   Article
8. The Frequency of Some Thrombophilic Mutations in Eastern Turkey.The Eurasian journal of medicine · 2016
   Article
9. Guidance for the evaluation and treatment of hereditary and acquired thrombophilia.Journal of thrombosis and thrombolysis · 2016
   Review
10. Role of thrombophilia testing: con.Journal of thrombosis and thrombolysis · 2015
    Review
11. Recurrent pregnancy loss in a subject with heterozygote factor V Leiden mutation; a case report.Reports of biochemistry & molecular biology · 2014
    Article
12. Processes and preliminary outputs for identification of actionable genes as incidental findings in genomic sequence data in the Clinical Sequencing Exploratory Research Consortium.Genetics in medicine : official journal of the American College of Medical Genetics · 2013
    Review
13. The importance of homozygous polymorphisms of methylenetetrahydrofolate reductase gene in romanian patients with idiopathic venous thromboembolism.Balkan medical journal · 2013
    Article
14. ACMG Practice Guideline: lack of evidence for MTHFR polymorphism testing.Genetics in medicine : official journal of the American College of Medical Genetics · 2013
    Article
15. Laboratory informatics based evaluation of methylene tetrahydrofolate reductase C677T genetic test overutilization.Journal of pathology informatics · 2013
    Article
16. Pharmacogenetic typing for oral anti-coagulant response among factor V Leiden mutation carriers.Indian journal of human genetics · 2012
    Article
17. Futility of testing for factor V Leiden.Blood transfusion = Trasfusione del sangue · 2012
    Article
18. Factor V Leiden: to test or not to test, that is the debate.Blood transfusion = Trasfusione del sangue · 2012
    Article
19. Utility of testing for factor V Leiden.Blood transfusion = Trasfusione del sangue · 2012
    Review
20. Replication and characterisation of genetic variants in the fibrinogen gene cluster with plasma fibrinogen levels and haematological traits in the Third National Health and Nutrition Examination Survey.Thrombosis and haemostasis · 2012
    Article

Corrections and comments

• Erratum issued
  Addendum: American College of Medical Genetics consensus statement on factor V Leiden mutation testing.2021

Authors and funding

6 authors.

Funding

No grant is acknowledged in the PubMed record.

Abstract

PubMed holds no abstract for this paper.

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