ReviewCanadian journal of psychiatry. Revue canadienne de psychiatrie2001
Genetic insights into schizophrenia.
Review in Canadian journal of psychiatry. Revue canadienne de psychiatrie, 2001. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
14 citing papers in PubMed.
- Evaluating genetic counseling for individuals with schizophrenia in the molecular age.Schizophrenia bulletin · 2014Article
- Evaluating genetic counseling for family members of individuals with schizophrenia in the molecular age.Schizophrenia bulletin · 2014Article
- Clinical applications of schizophrenia genetics: genetic diagnosis, risk, and counseling in the molecular era.The application of clinical genetics · 2012Article
- Clinically detectable copy number variations in a Canadian catchment population of schizophrenia.Journal of psychiatric research · 2010Article
- Identification of a schizophrenia-associated functional noncoding variant in NOS1AP.The American journal of psychiatry · 2009Article
- NOS1AP in schizophrenia.Current psychiatry reports · 2008Article
- Association of synapsin 2 with schizophrenia in families of Northern European ancestry.Schizophrenia research · 2007Article
- Increased expression in dorsolateral prefrontal cortex of CAPON in schizophrenia and bipolar disorder.PLoS medicine · 2005Article
- Genetic models of schizophrenia and bipolar disorder: overlapping inheritance or discrete genotypes?European archives of psychiatry and clinical neuroscience · 2005Review
- Tumor necrosis factor promoter haplotype associated with schizophrenia reveals a linked locus on 1q44.Molecular psychiatry · 2005Article
- Linkage disequilibrium mapping of schizophrenia susceptibility to the CAPON region of chromosome 1q22.American journal of human genetics · 2004Article
- Postmaturity in a genetic subtype of schizophrenia.Acta psychiatrica Scandinavica · 2003Article
- Schizophrenia and genetics: new insights.Current psychiatry reports · 2002Review
- Genetic counselling for schizophrenia in the era of molecular genetics.Canadian journal of psychiatry. Revue canadienne de psychiatrie · 2001Review
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4 authors.
Funding
Abstract
objectiveTo outline new insights into the genetic etiology of schizophrenia.
methodsWe discuss several commonly held beliefs about the genetic issues in schizophrenia.
resultsThe complex genetic nature of the illness poses a challenge for investigators seeking causative genetic mutations. Multiple independent research findings are, however converging to identify a relatively small number of chromosomal locations that appear to contain schizophrenia susceptibility genes. Also, a clinically relevant genetic subtype of schizophrenia (22qDS) has been identified. We are developing a better understanding of how schizophrenia relates to other psychiatric disorders. While investigations into the possible roles of dopaminergic and serotonergic systems continue, other approaches that do not require theories of the mechanism of illness are also being used to identify candidate susceptibility genes.
conclusionsResearch to date suggests that our understanding of the pathophysiology of schizophrenia will soon be fundamentally altered by genetic approaches to this complex disease.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.