Evidence map›Paper›PMID 11280080›Full record

ReviewCanadian journal of psychiatry. Revue canadienne de psychiatrie2001

Genetic counselling for schizophrenia in the era of molecular genetics.

K A Hodgkinson, J Murphy, S O'Neill, L Brzustowicz, A S Bassett

Registry-linked trialAbstract readReview
In one paragraph

Review in Canadian journal of psychiatry. Revue canadienne de psychiatrie, 2001. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00300820 (Seeking Genetic Counseling), which is not on this map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00300820 completednot on this mapstarted 2006, after this paper: background citation

Seeking Genetic Counseling: What Motivates Families At Risk For Psychiatric Illness?

TypeobservationalSponsorNational Human Genome Research Institute (NHGRI)Ran2006 to 2008Enrolled50ConditionsBipolar Disorder (BD), Bipolar
3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Evidence-Based Genetic Counseling for Psychiatric Disorders: A Road Map.Cold Spring Harbor perspectives in medicine · 2020
    Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Ethics and neuropsychiatric genetics: a review of major issues.The international journal of neuropsychopharmacology · 2012
    Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Schizophrenia and 22q11.2 deletion syndrome.Current psychiatry reports · 2008
    Review
  15. Article
  16. Review
  17. Article
  18. Clinical features of 78 adults with 22q11 Deletion Syndrome.American journal of medical genetics. Part A · 2005
    Article
  19. Review
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

K A HodgkinsonGenetics Department, Memorial University of Newfoundland, St John's, Newfoundland.
J Murphy
S O'Neill
L Brzustowicz
A S Bassett

Funding

CIHR 38099
6 · The paper itself

Abstract

objectiveTo review the role of genetic counselling for individuals with psychiatric illnesses.

methodUsing schizophrenia as an example and including updated information about a genetic subtype (22q deletion syndrome), we discuss the value of the genetic counselling process in psychiatry, with support from the literature and our clinical experience.

resultsGenetic counselling, the process through which knowledge about the genetics of illnesses is shared, provides information on the inheritance of illnesses and their recurrence risks; addresses the concerns of patients, their families, and their health care providers; and supports patients and their families dealing with these illnesses. For comprehensive medical management, this service should be available to all individuals with schizophrenia and their families.

conclusionsNew findings in the genetics of psychiatric illness may have important clinical implications for patients and their families.

Indexed as

Genetic CounselingMolecular BiologyChromosome DeletionChromosomes, Human, Pair 22HumansRisk FactorsSchizophrenia

Identifiers

PMID11280080
PMCPMC3276586

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.