Evidence map›Paper›PMID 11274119›Full record

ArticleJournal of bacteriology2001

Yersinia pestis pFra shows biovar-specific differences and recent common ancestry with a Salmonella enterica serovar Typhi plasmid.

M B Prentice, K D James, J Parkhill, S G Baker, K Stevens, M N Simmonds, K L Mungall, C Churcher, P C Oyston, R W Titball and 6 more

Open access · greenAbstract read
In one paragraph

Article in Journal of bacteriology, 2001. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.9field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 59 citations in OpenAlex.

  1. Optimised Heterologous Expression and Functional Analysis of theInternational journal of molecular sciences · 2021
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  14. Intraspecific diversity of Yersinia pestis.Clinical microbiology reviews · 2004
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 5 institutions in 2 countries.

M B PrenticeDepartment of Medical Microbiology, St. Bartholomew's and the Royal London School of Medicine and Dentistry, London, United Kingdom. m.b.prentice@mds.qmw.ac.uk
K D James
J Parkhill
S G Baker
K Stevens
M N Simmonds
K L Mungall
C Churcher
P C Oyston
R W Titball
B W Wren
J Wain
D Pickard
T T Hien
J J Farrar
G Dougan
Wellcome Sanger Institute · GBOxford University Clinical Research Unit · VNDefence Science and Technology Laboratory · GBImperial College London · GBLondon School of Hygiene & Tropical Medicine · GB

Funding

Wellcome Trust
6 · The paper itself

Abstract

Population genetic studies suggest that Yersinia pestis, the cause of plague, is a clonal pathogen that has recently emerged from Yersinia pseudotuberculosis. Plasmid acquisition is likely to have been a key element in this evolutionary leap from an enteric to a flea-transmitted systemic pathogen. However, the origin of Y. pestis-specific plasmids remains obscure. We demonstrate specific plasmid rearrangements in different Y. pestis strains which distinguish Y. pestis bv. Orientalis strains from other biovars. We also present evidence for plasmid-associated DNA exchange between Y. pestis and the exclusively human pathogen Salmonella enterica serovar Typhi.

Indexed as

Evolution, MolecularAnimalsDNA, BacterialDNA Transposable ElementsGene Transfer, HorizontalHumansMolecular Sequence DataPlasmidsPolymerase Chain ReactionSalmonella typhiSequence Analysis, DNAYersinia pestisDNA, BacterialDNA Transposable Elements

Identifiers

PMID11274119
PMCPMC95176
OpenAlexW2005569412

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.