ArticleBiophysical journal2001
Effects of excluded surface area and adsorbate clustering on surface adsorption of proteins. II. Kinetic models.
Article in Biophysical journal, 2001. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed.
- Biocompatibility in hemodialysis: artificial membrane and human blood interactions.BMC nephrology · 2025Review
- Oligomerization of peripheral membrane proteins provides tunable control of cell surface polarity.Biophysical journal · 2022Article
- Water Loss in Aging Erythrocytes Provides a Clue to a General Mechanism of Cellular Senescence.Biophysical journal · 2020Review
- Protein Adsorption and Layer Formation at the Stainless Steel-Solution Interface Mediates Shear-Induced Particle Formation for an IgG1 Monoclonal Antibody.Molecular pharmaceutics · 2018Article
- Physical biology of the cancer cell glycocalyx.Nature physics · 2018Article
- Impact of GMBiophysical journal · 2017Review
- Kinetics of Surface-Driven Self-Assembly and Fatigue-Induced Disassembly of a Virus-Based Nanocoating.Biophysical journal · 2017Article
- Reversible Adsorption Kinetics of Near Surface Dimer Colloids.Langmuir : the ACS journal of surfaces and colloids · 2016Article
- GM1 Ganglioside Inhibits β-Amyloid Oligomerization Induced by Sphingomyelin.Angewandte Chemie (International ed. in English) · 2016Article
- Enhancement of biological reactions on cell surfaces via macromolecular crowding.Nature communications · 2014Article
- Dynamics and instabilities of lipid bilayer membrane shapes.Advances in colloid and interface science · 2014Review
- A bottom-up approach to understanding protein layer formation at solid-liquid interfaces.Advances in colloid and interface science · 2014Review
- Interfacial protein-protein associations.Biomacromolecules · 2014Article
- Engineering lipid bilayer membranes for protein studies.International journal of molecular sciences · 2013Review
- Curvature sorting of proteins on a cylindrical lipid membrane tether connected to a reservoir.Physical review. E, Statistical, nonlinear, and soft matter physics · 2012Article
- Article
- Quantitative experimental assessment of macromolecular crowding effects at membrane surfaces.Biophysical journal · 2010Article
- The role of mass transport limitation and surface heterogeneity in the biophysical characterization of macromolecular binding processes by SPR biosensing.Methods in molecular biology (Clifton, N.J.) · 2010Review
- Macromolecular crowding and confinement: biochemical, biophysical, and potential physiological consequences.Annual review of biophysics · 2008Review
- How Surface Heterogeneity Affects Protein Adsorption: Annealing of OTS Patterns and Albumin Adsorption Kinetics.Croatica chemica acta. Arhiv za kemiju · 2007Article
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Abstract
Models for equilibrium surface adsorption of proteins have been recently proposed (Minton, A. P., 2000. Biophys. Chem. 86:239-247) in which negative cooperativity due to area exclusion by adsorbate molecules is compensated to a variable extent by the formation of a heterogeneous population of monolayer surface clusters of adsorbed protein molecules. In the present work this concept is extended to treat the kinetics of protein adsorption. It is postulated that clusters may grow via two distinct kinetic pathways. The first pathway is the diffusion of adsorbed monomer to the edge of a preexisting cluster and subsequent accretion. The second pathway consists of direct deposition of a monomer in solution onto the upper (solution-facing) surface of a preexisting cluster ("piggyback" deposition) and subsequent incorporation into the cluster. Results of calculations of the time course of adsorption, carried out for two different limiting models of cluster structure and energetics, show that in the absence of piggyback deposition, enhancement of the tendency of adsorbate to cluster can reduce, but not eliminate, the negative kinetic cooperativity due to surface area exclusion by adsorbate. Apparently noncooperative (Langmuir-like) and positively cooperative adsorption progress curves, qualitatively similar to those reported in several published experimental studies, require a significant fraction of total adsorption flux through the piggyback deposition pathway. According to the model developed here and in the above-mentioned reference, the formation of surface clusters should be a common concomitant of non-site-specific surface adsorption of proteins, and may provide an important mechanism for assembly of organized "protein machines" in vivo.
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