Evidence map›Paper›PMID 11254651›Full record

ArticleInfection and immunity2001

HLA-A*01-restricted cytotoxic T-lymphocyte epitope from the Plasmodium falciparum circumsporozoite protein.

A Kumar, S Kumar, T P Le, S Southwood, J Sidney, J Cohen, A Sette, S L Hoffman

Abstract read
In one paragraph

Article in Infection and immunity, 2001. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Comprehensive Review of HumanFrontiers in immunology · 2019
    Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 1 country.

A KumarMalaria Program, Naval Medical Research Center, Silver Spring, Maryland 20910-7500, USA. kumara@nmrc.navy.mil
S Kumar
T P Le
S Southwood
J Sidney
J Cohen
A Sette
S L Hoffman
Autoimmune Technologies (United States) · USNaval Medical Research Command · USJackson Foundation · USJohns Hopkins University · USNew Frontier · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Here, we report the identification of a novel CD8+ cytotoxic T-lymphocyte epitope on the Plasmodium falciparum circumsporozoite protein (3D7; amino acids 310 to 319 [EPSDKHIKEY]) that is restricted by HLA-A*01 and is recognized by human volunteers immunized with irradiated P. falciparum sporozoites. HLA-A*01 is the second most common HLA allele among Caucasians.

Indexed as

Epitopes, T-LymphocyteAllelesAmino Acid SequenceAnimalsHLA-A AntigensHumansImmunizationMolecular Sequence DataPeptide FragmentsPlasmodium falciparumProtozoan ProteinsT-Lymphocytes, Cytotoxiccircumsporozoite protein, ProtozoanEpitopes, T-LymphocyteHLA-A AntigensPeptide FragmentsProtozoan Proteins

Identifiers

PMID11254651
PMCPMC98223
OpenAlexW2145472004

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.