ReviewMolecular biotechnology2000
Epoxygenase metabolites. Epithelial and vascular actions.
Review in Molecular biotechnology, 2000. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
9 citing papers in PubMed, 46 citations in OpenAlex.
- PTUPB, a soluble epoxide hydrolase/cyclooxygenase‑2 dual inhibitor, reduces endothelial‑to‑mesenchymal transition and improves doxorubicin‑induced vascular and cardiac toxicity.Molecular medicine reports · 2026Article
- Inactivation of CysBritish journal of pharmacology · 2020Article
- Association ofJournal of diabetes research · 2018Article
- Anti-inflammatory effects of ω-3 polyunsaturated fatty acids and soluble epoxide hydrolase inhibitors in angiotensin-II-dependent hypertension.Journal of cardiovascular pharmacology · 2013Article
- Determination of the dominant arachidonic acid cytochrome p450 monooxygenases in rat heart, lung, kidney, and liver: protein expression and metabolite kinetics.The AAPS journal · 2013Article
- Cytochrome P450 2C24: Expression, Tissue Distribution, High-Throughput Assay, and Pharmacological Inhibition.Acta pharmaceutica Sinica. B · 2012Article
- Interaction between alcohol consumption and CYP 2C19 gene polymorphism in relation to oesophageal squamous cell carcinoma.PloS one · 2012Article
- CYP4A11 T8590C polymorphism, salt-sensitive hypertension, and renal blood flow.Journal of hypertension · 2011Article
- Mitogenic activity and signaling mechanism of 2-(14,15- epoxyeicosatrienoyl)glycerol, a novel cytochrome p450 arachidonate metabolite.Molecular and cellular biology · 2007Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
Abstract
Cytochrome P450 (CYP450) epoxygenase enzymes demonstrate organ and cell specific expression and each CYP450 enzyme isoform produces a distinct pattern of epoxyeicosatrienoic acids (EETs). Investigations are beginning to describe the regulation of specific tissue CYP450 epoxygenase isoforms that may be associated with alterations in organ function that occur during various physiological and pathophysiological states. The main biological actions of EETs are their ability to affect epithelial ion transport and vascular smooth muscle cell function. This chapter focuses on the organ localization and production of EETs and the action of EETs on epithelial and vascular smooth muscle cells.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.