Evidence map›Paper›PMID 11250744›Full record

ReviewBreast cancer research : BCR2001

Probing physiology and molecular function using optical imaging: applications to breast cancer.

V Ntziachristos, B Chance

Open access · goldAbstract readReview
In one paragraph

Review in Breast cancer research : BCR, 2001. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 57 papers.

0numbers the graph read from it
0cells of the map it votes in
57citing papers in PubMed
14.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

57 citing papers in PubMed, 249 citations in OpenAlex.

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  17. Nanoparticles for multimodal in vivo imaging in nanomedicine.International journal of nanomedicine · 2014
    Review
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  20. Fluorescence Intensity and Lifetime Cell Imaging with Luminescent Gold Nanoclusters.The journal of physical chemistry. C, Nanomaterials and interfaces · 2012
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

V NtziachristosDepartment of Bioengineering, University of Pennsylvania, Philadelphia, USA. vasilis@helix.mgh.harvard.edu
B Chance
University of Pennsylvania · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The present review addresses the capacity of optical imaging to resolve functional and molecular characteristics of breast cancer. We focus on recent developments in optical imaging that allow three-dimensional reconstruction of optical signatures in the human breast using diffuse optical tomography (DOT). These technologic advances allow the noninvasive, in vivo imaging and quantification of oxygenated and deoxygenated hemoglobin and of contrast agents that target the physiologic and molecular functions of tumors. Hence, malignancy differentiation can be based on a novel set of functional features that are complementary to current radiologic imaging methods. These features could enhance diagnostic accuracy, lower the current state-of-the-art detection limits, and play a vital role in therapeutic strategy and monitoring.

Indexed as

Magnetic Resonance ImagingBreast NeoplasmsContrast MediaDiagnostic ImagingFemaleFluorescenceGenetic MarkersHumansImmunoenzyme TechniquesModels, BiologicalOptics and PhotonicsPhantoms, ImagingTransilluminationUltrasonographyContrast MediaGenetic Markers

Identifiers

PMID11250744
PMCPMC150034
OpenAlexW2170076318

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.