ReviewBreast cancer research : BCR2000
Molecular biology of breast cancer metastasis. Molecular expression of vascular markers by aggressive breast cancer cells.
Review in Breast cancer research : BCR, 2000. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
33 citing papers in PubMed.
- HP1a-mediated heterochromatin formation inhibits high dietary sugar-induced tumor progression.Cell death & disease · 2021Article
- Engineering a Novel 3D Printed Vascularized Tissue Model for Investigating Breast Cancer Metastasis to Bone.Advanced healthcare materials · 2020Article
- Article
- Advances and Prospects of Vasculogenic Mimicry in Glioma: A Potential New Therapeutic Target?OncoTargets and therapy · 2020Review
- Breast tumor classification using different features of quantitative ultrasound parametric images.International journal of computer assisted radiology and surgery · 2019Article
- Article
- Angiogenesis and vasculogenic mimicry are inhibited by 8-Br-cAMP through activation of the cAMP/PKA pathway in colorectal cancer.OncoTargets and therapy · 2018Article
- Targeting the Stem Cell Properties of Adult Breast Cancer Cells: Using Combinatorial Strategies to Overcome Drug Resistance.Current molecular biology reports · 2017Article
- Downregulation of transgelin blocks interleukin-8 utilization and suppresses vasculogenic mimicry in breast cancer cells.Experimental biology and medicine (Maywood, N.J.) · 2017Article
- Paracrine effect of GTP cyclohydrolase and angiopoietin-1 interaction in stromal fibroblasts on tumor Tie2 activation and breast cancer growth.Oncotarget · 2016Article
- Claudin-4 is required for vasculogenic mimicry formation in human breast cancer cells.Oncotarget · 2015Article
- Merkel cell carcinoma expresses vasculogenic mimicry: demonstration in patients and experimental manipulation in xenografts.Laboratory investigation; a journal of technical methods and pathology · 2014Article
- Vasculogenic mimicry contributes to lymph node metastasis of laryngeal squamous cell carcinoma.Journal of experimental & clinical cancer research : CR · 2010Article
- Breast carcinomatous tumoral emboli can result from encircling lymphovasculogenesis rather than lymphovascular invasion.Oncotarget · 2010Article
- Spheroid-forming subpopulation of breast cancer cells demonstrates vasculogenic mimicry via hsa-miR-299-5p regulated de novo expression of osteopontin.Journal of cellular and molecular medicine · 2010Article
- Article
- Article
- The antiangiogenic agent ZD4190 prevents tumour outgrowth in a model of minimal residual carcinoma in deep tissues.British journal of cancer · 2009Article
- Role of Sox-9, ER81 and VE-cadherin in retinoic acid-mediated trans-differentiation of breast cancer cells.PloS one · 2008Article
- Glypican-1 modulates the angiogenic and metastatic potential of human and mouse cancer cells.The Journal of clinical investigation · 2008Article
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4 authors.
Funding
Abstract
During embryogenesis, the formation of primary vascular networks occurs via the processes of vasculogenesis and angiogenesis. In uveal melanoma, vasculogenic mimicry describes the 'embryonic-like' ability of aggressive, but not nonaggressive, tumor cells to form networks surrounding spheroids of tumor cells in three-dimensional culture; these recapitulate the patterned networks seen in patients' aggressive tumors and correlates with poor prognosis. The molecular profile of these aggressive tumor cells suggests that they have a deregulated genotype, capable of expressing vascular phenotypes. Similarly, the embryonic-like phenotype expressed by the aggressive human breast cancer cells is associated with their ability to express a variety of vascular markers. These studies may offer new insights for consideration in breast cancer diagnosis and therapeutic intervention strategies.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.