Trial reportThe Journal of clinical psychiatry2001
Delusionality and response to open-label fluvoxamine in body dysmorphic disorder.
Trial report in The Journal of clinical psychiatry, 2001. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 1 synthesis or guideline pooled it, 160 citations in OpenAlex.
- Pharmacotherapy and psychotherapy for body dysmorphic disorder.The Cochrane database of systematic reviews · 2009Pooled it
- Depression, anxiety, anger, and somatic symptoms in patients with body dysmorphic disorder.The Psychiatric quarterly · 2004Trial
- Insight in obsessive compulsive disorder and body dysmorphic disorder.Comprehensive psychiatryTrial
- Links Between Body Dysmorphic Disorder (BDD) With Aesthetic Components of Orthodontic Treatment Need Assessed by Orthodontic Patients or Orthodontists (IOTN-AC, IOTN-ACE) and Also With Its Risk Factors: An Epidemiological Cross-Sectional Study.Health science reports · 2026Article
- Emotion regulation and visual attention in body dysmorphic disorder: a multimodal study using EEG, GSR, and eye-tracking.BMC psychiatry · 2026Article
- Shame-related disorders in patients with atopic dermatitis and psoriasis - An exploratory, cross-sectional interview study on the prevalence and correlates of body dysmorphic disorder and social anxiety disorder.Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG · 2026Article
- Psychological Disorders Are a Non-negligible Factor in Medical Aesthetic Disputes.Aesthetic plastic surgery · 2026Review
- Associations between body dysmorphic disorder (BDD) with the dental health component of the index of orthodontic treatment need (IOTN-DHC) and other BDD risk factors in orthodontic patients: A preliminary study.Korean journal of orthodontics · 2023Article
- Reliability and Validity of the Self-Report Chinese Version of the Yale-Brown Obsessive-Compulsive Scale Modified for Body Dysmorphic Disorder (BDD-YBOCS) in Patients Undergoing Plastic Surgery.Aesthetic plastic surgery · 2022Article
- Psychiatric Assessment and Management of Clients Undergoing Cosmetic Surgery: Overview and Need for an Integrated Approach.Indian journal of plastic surgery : official publication of the Association of Plastic Surgeons of India · 2021Review
- Cosmetic Surgery and Body Dysmorphic Disorder - An Update.International journal of women's dermatology · 2018Review
- Delusional versus nondelusional body dysmorphic disorder: recommendations for DSM-5.CNS spectrums · 2014Review
- A comparison of insight in body dysmorphic disorder and obsessive-compulsive disorder.Journal of psychiatric research · 2012Article
- [Psychopharmacological treatment in patients with somatoform disorders and functional body syndromes].Der Nervenarzt · 2012Article
- Perceived ugliness: an update on treatment-relevant aspects of body dysmorphic disorder.Current psychiatry reports · 2011Review
- Cognitive-behavioral therapy for youth with body dysmorphic disorder: current status and future directions.Child and adolescent psychiatric clinics of North America · 2011Review
- Relationship between social anxiety disorder and body dysmorphic disorder.Clinical psychology review · 2010Review
- Pharmacotherapy for Body Dysmorphic Disorder.Psychiatric annals · 2010Article
- Body dysmorphic disorder: some key issues for DSM-V.Depression and anxiety · 2010Review
- Treating body dysmorphic disorder with medication: evidence, misconceptions, and a suggested approach.Body image · 2008Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
backgroundAvailable data suggest that the delusional variant of body dysmorphic disorder (BDD), a type of delusional disorder, may respond to serotonin reuptake inhibitors (SRIs) and that delusionality (lack of insight) in BDD may improve with SRI treatment. However, this research has been hampered by the lack of a reliable and valid scale to assess delusionality.
methodThirty subjects (21 women, 9 men; mean age = 33.3 +/- 9.0 years) with DSM-IV BDD were prospectively treated with open-label fluvoxamine for 16 weeks. Subjects were assessed at regular intervals with the Brown Assessment of Beliefs Scale (BABS), the Yale-Brown Obsessive Compulsive Scale Modified for BDD (BDD-YBOCS; a measure of BDD severity), and other instruments. The BABS is a reliable and valid 7-item, semistructured, clinician-administered scale that assesses current delusionality.
resultsIn this prospective, open-label study, 63% of BDD subjects responded to fluvoxamine. Delusional and nondelusional subjects had similar improvement in BDD symptoms. In addition, insight significantly improved in both delusional and nondelusional subjects. Baseline BABS scores did not contribute significantly to endpoint BDD-YBOCS scores in a regression analysis.
conclusionDegree of delusionality did not predict fluvoxamine response, and delusionality significantly improved. These findings are preliminary and require confirmation in controlled trials. The implications of these findings for other types of delusions requires investigation.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.