ReviewJournal of neuro-oncology
Antiangiogenesis -- therapeutic strategies and clinical implications for brain tumors.
Review in Journal of neuro-oncology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed.
- Phase 2 trial of copper depletion and penicillamine as antiangiogenesis therapy of glioblastoma.Neuro-oncology · 2005Trial
- Article
- Loss of Complement Factor H in Plasma Increases Endothelial Cell Migration.Journal of Cancer · 2017Article
- Asn-Gly-Arg-modified polydopamine-coated nanoparticles for dual-targeting therapy of brain glioma in rats.Oncotarget · 2016Article
- Discrimination between two different grades of human glioma based on blood vessel infrared spectral imaging.Analytical and bioanalytical chemistry · 2015Article
- Article
- The immunopharmacologic potential of Semaxanib and new generation directed therapeutic drugs: Receptor tyrosine kinase regulation with anti-tumorigenensis/angiogenesis properties.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2012Article
- Antitumor efficacy of a novel CLA-PTX microemulsion against brain tumors: in vitro and in vivo findings.International journal of nanomedicine · 2012Article
- Expression of VEGF and MMP-9 and MRI imaging changes in cerebral glioma.Oncology letters · 2011Article
- Gene therapy and targeted toxins for glioma.Current gene therapy · 2011Review
- Nanoparticles of carbon allotropes inhibit glioblastoma multiforme angiogenesis in ovo.International journal of nanomedicine · 2011Article
- Inhibitory effects of TNP-470 in combination with BCNU on tumor growth of human glioblastoma xenografts.Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban · 2010Article
- Adeno-associated virus-mediated delivery of kringle 5 of human plasminogen inhibits orthotopic growth of ovarian cancer.Gene therapy · 2010Article
- Targeting angiogenesis in pancreatic cancer: rationale and pitfalls.Langenbeck's archives of surgery · 2008Review
- Successful inhibition of intracranial human glioblastoma multiforme xenograft growth via systemic adenoviral delivery of soluble endostatin and soluble vascular endothelial growth factor receptor-2: laboratory investigation.Journal of neurosurgery · 2008Article
- Type I collagen gene suppresses tumor growth and invasion of malignant human glioma cells.Cancer cell international · 2007Article
- Variable deficiencies in the interferon response enhance susceptibility to vesicular stomatitis virus oncolytic actions in glioblastoma cells but not in normal human glial cells.Journal of virology · 2007Article
- S100A13, a new marker of angiogenesis in human astrocytic gliomas.Journal of neuro-oncology · 2006Article
- Mechanisms of angiogenesis in gliomas.Journal of neuro-oncology · 2006Review
- Advances in treatment of pediatric brain tumors.NeuroRx : the journal of the American Society for Experimental NeuroTherapeutics · 2006Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The poor prognosis of patients with malignant brain tumors in spite of aggressive multimodality therapy has led to the search for novel therapeutic strategies. Among the targets for such treatment approaches, tumor angiogenesis has captured the attention of not only the medical field but also of the lay public because of its conceptual departure from traditional methods of cancer therapy. Angiogenesis and vascular proliferation are particularly important in the growth and progression of malignant gliomas and are used as indicators of the degree of malignancy. Recent studies have helped us gain a better understanding of the molecular mediators of this process. It is now evident that after the initial formation of malignancy the continued growth of a glioma is critically dependent on its angiogenic potential. Hence, several approaches to control angiogenesis are being developed and tested. In the present review, we examine some of these approaches from a therapeutic perspective and summarize the findings from early human trials of such agents.
Indexed as
Identifiers
11245279What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.