ArticlePlant physiology2001
Nonsense-mediated decay of mutant waxy mRNA in rice.
Article in Plant physiology, 2001. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
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Who cites it
27 citing papers in PubMed, 97 citations in OpenAlex.
- ThreeInternational journal of molecular sciences · 2023Article
- Fast and Inexpensive Phenotyping and Genotyping Methods for Evaluation of Barley Mutant Population.Plants (Basel, Switzerland) · 2020Article
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- Three Major Nucleotide Polymorphisms in theJournal of applied glycoscience · 2019Article
- A deletion of the gene encoding amino aldehyde dehydrogenase enhances the "pandan-like" aroma of winter melon (Benincasa hispida) and is a functional marker for the development of the aroma.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2017Article
- Genome Engineering and Agriculture: Opportunities and Challenges.Progress in molecular biology and translational science · 2017Review
- Analysis of the Rice ADP-Glucose Transporter (OsBT1) Indicates the Presence of Regulatory Processes in the Amyloplast Stroma That Control ADP-Glucose Flux into Starch.Plant physiology · 2016Article
- NMD mechanism and the functions of Upf proteins in plant.Plant cell reports · 2016Review
- Nonsense-mediated mRNA degradation of CtFAD2-1 and development of a perfect molecular marker for olol mutation in high oleic safflower (Carthamus tinctorius L.).TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2013Article
- Splicing and alternative splicing in rice and humans.BMB reports · 2013Review
- Translational Regulation of Cytoplasmic mRNAs.The arabidopsis book · 2013Article
- High resolution melting analysis for the detection of EMS induced mutations in wheat SBEIIa genes.BMC plant biology · 2011Article
- Two solanesyl diphosphate synthases with different subcellular localizations and their respective physiological roles in Oryza sativa.Journal of experimental botany · 2010Article
- An expression analysis of the ascorbate biosynthesis enzyme VTC2.Plant molecular biology · 2008Article
- The M flax rust resistance pre-mRNA is alternatively spliced and contains a complex upstream untranslated region.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2007Article
- A novel wx mutation caused by insertion of a retrotransposon-like sequence in a glutinous cultivar of rice (Oryza sativa).TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2007Article
- Comprehensive analysis of alternative splicing in rice and comparative analyses with Arabidopsis.BMC genomics · 2006Article
- Recessiveness and dominance in barley mutants deficient in Mg-chelatase subunit D, an AAA protein involved in chlorophyll biosynthesis.The Plant cell · 2006Article
- The serine/arginine-rich protein family in rice plays important roles in constitutive and alternative splicing of pre-mRNA.The Plant cell · 2006Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Two rice (Oryza sativa) waxy mutations of the Japonica background were shown to contain approximately 20% of the fully spliced mRNA relative to the wild type. Sequencing analysis of the entire waxy genes of the two mutants revealed the presence of premature translation termination codons in exon 2 and exon 7. These results indicated that the lower accumulation of fully spliced RNA in the mutants was caused by nonsense-mediated decay (NMD), which is an RNA surveillance system universally found in eukaryotes. It is interesting that levels of RNA retaining intron 1 were not changed by premature nonsense codons, suggesting that splicing may be linked with NMD in plants, as previously found in mammalian cells. Measurements of the half-lives of waxy RNAs in transfected rice protoplasts indicated that the half-life of waxy RNA with a premature nonsense codon was 3.3 times shorter than that without a premature nonsense codon. Because the wild-type waxy transcripts, which are derived from the Wx(b) gene predominantly distributed among Japonica rice, have been shown to be less efficiently spliced and their alternative splicing has been documented, we examined whether these splicing properties influenced the efficiency of NMD. However, no effects were observed. These results established that NMD occurs in rice waxy RNA containing a premature nonsense codon.
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