ArticlePlant physiology2001
Quantitative trait locus mapping of loci influencing elongation factor 1alpha content in maize endosperm.
Article in Plant physiology, 2001. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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12 citing papers in PubMed, 45 citations in OpenAlex.
- Genetic engineering to improve essential and conditionally essential amino acids in maize: transporter engineering as a reference.Transgenic research · 2021Article
- Identification of the quantitative trait loci (QTL) underlying water soluble protein content in soybean.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2013Article
- Gamma-zeins are essential for endosperm modification in quality protein maize.Proceedings of the National Academy of Sciences of the United States of America · 2010Article
- Quantitative trait loci controlling sulfur containing amino acids, methionine and cysteine, in soybean seeds.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2006Article
- Identification and validation of QTLs conferring resistance to sorghum downy mildew (Peronosclerospora sorghi) and Rajasthan downy mildew (P. heteropogoni) in maize.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2005Article
- Identification and characterization of a QTL on chromosome 2 for cytosolic glutamine synthetase content and panicle number in rice.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2004Article
- Article
- Cytoskeletal proteins are coordinately increased in maize genotypes with high levels of eEF1A.Plant physiology · 2004Article
- eEF1A isoforms change in abundance and actin-binding activity during maize endosperm development.Plant physiology · 2003Article
- Statistical methods for dissecting triploid endosperm traits using molecular markers. An autogamous model.Genetics · 2002Article
- An improved genetic model generates high-resolution mapping of QTL for protein quality in maize endosperm.Proceedings of the National Academy of Sciences of the United States of America · 2002Article
- Genetic analysis of amino acid accumulation in opaque-2 maize endosperm.Plant physiology · 2001Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The nutritional value of maize (Zea mays) seed is most limited by its protein quality because its storage proteins are devoid of the essential amino acid lysine (Lys). The Lys content of the kernel can be significantly increased by the opaque-2 mutation, which reduces zein synthesis and increases accumulation of proteins that contain Lys. Elongation factor 1alpha (eEF1A) is one of these proteins, and its concentration is highly correlated with the Lys content of the endosperm. We investigated the genetic regulation of eEF1A and the basis for its relationship with other Lys-containing proteins by analyzing the progeny of a cross between a high (Oh51Ao2) and a low (Oh545o2) eEF1A maize inbred. We identified 83 simple sequence repeat loci that are polymorphic between these inbreds; the markers are broadly distributed over the genome (1,402 cM) with an average interval of 17 cM. Genotypic analysis of the F(2) progeny revealed two significant quantitative trait loci that account for 25% of the variance for eEF1A content. One of these is on the short arm of chromosome 4 and is linked with a cluster of 22-kD alpha-zein coding sequences; the other quantitative trait locus is on the long arm of chromosome 7. The content of alpha-zein and gamma-zein was measured in pools of high- and low-eEF1A individuals obtained from this cross, and a higher level of alpha-zein was found to cosegregate with high eEF1A content. Allelic variation at the 22-kD alpha-zein locus may contribute to the difference of eEF1A content between Oh51Ao2 and Oh545o2 by increasing the surface area of protein bodies in the endosperm and creating a more extensive network of cytoskeletal proteins.
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