ArticleThe Korean journal of internal medicine2000
New ADA criteria in the Korean population: fasting blood glucose is not enough for diagnosis of mild diabetes especially in the elderly.
Article in The Korean journal of internal medicine, 2000. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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6 citing papers in PubMed.
- Evolving Characteristics of Type 2 Diabetes Mellitus in East Asia.Endocrinology and metabolism (Seoul, Korea) · 2025Review
- Pathogenesis of type 2 diabetes in Japan and East Asian populations: Basic and clinical explorations.Proceedings of the Japan Academy. Series B, Physical and biological sciences · 2025Review
- The spontaneous-diabetes rat: a model of noninsulin dependent diabetes mellitus by Yoshio Goto and Masaei Kakizaki (1981).Proceedings of the Japan Academy. Series B, Physical and biological sciences · 2024Review
- Effects of insulin resistance and β-cell function on diabetic complications in Korean diabetic patients.PloS one · 2024Article
- The Prevalence and Characteristics of Exocrine Pancreatic Insufficiency in Patients with Type 2 Diabetes: A Systematic Review and Meta-Analysis.International journal of endocrinology · 2022Review
- β cell dysfunction versus insulin resistance in the pathogenesis of type 2 diabetes in East Asians.Current diabetes reports · 2015Article
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Abstract
backgroundTo compare the 1997 American Diabetes Association (ADA) criteria with the 1985 World Health Organization (WHO) criteria in categorization of the diabetes diagnostic status of Koreans and to define clinical characteristics of subjects diagnosed differently by the two criteria.
methodsIn 810 Korean subjects, we analyzed blood glucose and insulin response during 75 g oral glucose tolerance test (OGTT). According to current WHO criteria, the cutoff values of FPG which distinguish normal and IGT from diabetes were determined. Then the subjects were categorized according to both WHO and ADA criteria. The clinical characteristics of the subjects with different diagnostic categories by the two criteria were defined.
resultsThe FPG cut point distinguishing diabetes from IGT was 117 mg/dl, and from normal was 110 mg/dl. The overall agreement between the ADA criteria and the WHO criteria was moderate, as reflected in the kappa of 0.45. 141 of subjects categorized diabetes by WHO criteria were not diagnosed with ADA criteria. These discordant subjects were older in age and showed blunted early insulin response than concordant normal subjects.
conclusionThese results suggest that mild diabetes by the WHO criteria, especially in the elderly, would not be diagnosed as diabetes by the ADA FPG criteria only. Thus, in a group at high risk for developing diabetes or in a relatively older age group, we should continue using the OGTT.
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