Evidence map›Paper›PMID 11241345›Full record

ReviewJournal of cellular physiology2001

Eukaryotic ribonuclease P: increased complexity to cope with the nuclear pre-tRNA pathway.

S Xiao, F Houser-Scott, D R Engelke

Open access · greenAbstract readReview
In one paragraph

Review in Journal of cellular physiology, 2001. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 47 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Structure of Pfu Pop5, an archaeal RNase P protein.Proceedings of the National Academy of Sciences of the United States of America · 2006
    Article
  7. Article
  8. Article
  9. Article
  10. Structure of Mth11/Mth Rpp29, an essential protein subunit of archaeal and eukaryotic RNase P.Proceedings of the National Academy of Sciences of the United States of America · 2003
    Article
  11. Article
  12. Article
  13. Interactions among the protein and RNA subunits of Saccharomyces cerevisiae nuclear RNase P.Proceedings of the National Academy of Sciences of the United States of America · 2002
    Article
  14. Article
  15. Review
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

S XiaoDepartment of Biological Chemistry, The University of Michigan Medical School, Ann Arbor, Michigan 48109-0606 USA.
F Houser-Scott
D R Engelke
University of Michigan–Ann Arbor · US

Funding

EUKARYOTIC TRNA MATURATIONR01GM034869 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI ENGELKE, DAVID R · 1985 to 2006
$2.3M
NIGMS NIH HHS GM-34869NIGMS NIH HHS R01 GM034869
6 · The paper itself

Abstract

Ribonuclease P is an ancient enzyme that cleaves pre-tRNAs to generate mature 5' ends. It contains an essential RNA subunit in Bacteria, Archaea, and Eukarya, but the degree to which the RNA subunit relies on proteins to supplement catalysis is highly variable. The eukaryotic nuclear holoenzyme has recently been found to contain almost twenty times the protein content of the bacterial enzymes, in addition to having split into at least two related enzymes with distinct substrate specificity. In this review, recent progress in understanding the molecular architecture and functions of nuclear forms of RNase P will be considered.

Indexed as

RNA Processing, Post-TranscriptionalAnimalsBiological EvolutionCell NucleusEndoribonucleasesMacromolecular SubstancesNucleic Acid ConformationRibonuclease PRNA, CatalyticRNA PrecursorsRNA, TransferSaccharomyces cerevisiaeSubstrate SpecificityEndoribonucleasesMacromolecular Substancesmitochondrial RNA-processing endoribonucleaseRibonuclease PRNA, CatalyticRNA PrecursorsRNA, Transfer

Identifiers

PMID11241345
PMCPMC3758117
OpenAlexW1977749262

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.