ArticleGenetics2001
Analysis of expressed sequence tags from two starvation, time-of-day-specific libraries of Neurospora crassa reveals novel clock-controlled genes.
Article in Genetics, 2001. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
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Who cites it
34 citing papers in PubMed.
- Identification of Circadian Clock Homologs and Their Rhythmic Expression Differences Among Mating-Type Strains inJournal of fungi (Basel, Switzerland) · 2026Article
- The Evolutionary and Functional Paradox of Cerato-platanins in Fungi.Applied and environmental microbiology · 2020Article
- A HAD family phosphatase CSP-6 regulates the circadian output pathway in Neurospora crassa.PLoS genetics · 2018Article
- Modulation of Circadian Gene Expression and Metabolic Compensation by the RCO-1 Corepressor of Neurospora crassa.Genetics · 2016Article
- The circadian system as an organizer of metabolism.Fungal genetics and biology : FG & B · 2016Review
- Analysis of Circadian Rhythms in the Basal Filamentous Ascomycete Pyronema confluens.G3 (Bethesda, Md.) · 2015Article
- Dissecting the mechanisms of the clock in Neurospora.Methods in enzymology · 2015Review
- Analysis of clock-regulated genes in Neurospora reveals widespread posttranscriptional control of metabolic potential.Proceedings of the National Academy of Sciences of the United States of America · 2014Article
- Circadian activation of the mitogen-activated protein kinase MAK-1 facilitates rhythms in clock-controlled genes in Neurospora crassa.Eukaryotic cell · 2013Article
- Sex-specific gene expression during asexual development of Neurospora crassa.Fungal genetics and biology : FG & B · 2012Article
- The Neurospora crassa OS MAPK pathway-activated transcription factor ASL-1 contributes to circadian rhythms in pathway responsive clock-controlled genes.Fungal genetics and biology : FG & B · 2012Article
- The genetics of circadian rhythms in Neurospora.Advances in genetics · 2011Review
- Generation and analysis of expressed sequence tags from a cDNA library of the fruiting body of Ganoderma lucidum.Chinese medicine · 2010Article
- Circadian rhythmicity mediated by temporal regulation of the activity of p38 MAPK.Proceedings of the National Academy of Sciences of the United States of America · 2007Article
- Gene discovery and transcript analyses in the corn smut pathogen Ustilago maydis: expressed sequence tag and genome sequence comparison.BMC genomics · 2007Article
- Analysis of expressed sequence tags from the fungus Aspergillus oryzae cultured under different conditions.DNA research : an international journal for rapid publication of reports on genes and genomes · 2007Article
- Circadian output, input, and intracellular oscillators: insights into the circadian systems of single cells.Cold Spring Harbor symposia on quantitative biology · 2007Review
- Enabling a community to dissect an organism: overview of the Neurospora functional genomics project.Advances in genetics · 2007Review
- Circadian rhythms in Neurospora crassa and other filamentous fungi.Eukaryotic cell · 2006Review
- Comparative EST analysis provides insights into the basal aquatic fungus Blastocladiella emersonii.BMC genomics · 2006Article
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Authors and funding
10 authors.
Funding
Abstract
In an effort to determine genes that are expressed in mycelial cultures of Neurospora crassa over the course of the circadian day, we have sequenced 13,000 cDNA clones from two time-of-day-specific libraries (morning and evening library) generating approximately 20,000 sequences. Contig analysis allowed the identification of 445 unique expressed sequence tags (ESTs) and 986 ESTs present in multiple cDNA clones. For approximately 50% of the sequences (710 of 1431), significant matches to sequences in the National Center for Biotechnology Information database (of known or unknown function) were detected. About 50% of the ESTs (721 of 1431) showed no similarity to previously identified genes. We hybridized Northern blots with probes derived from 26 clones chosen from contigs identified by multiple cDNA clones and EST sequences. Using these sequences, the representation of genes among the morning and evening sequences, respectively, in most cases does not reflect their expression patterns over the course of the day. Nevertheless, we were able to identify four new clock-controlled genes. On the basis of these data we predict that a significant proportion of the expressed Neurospora genes may be regulated by the circadian clock. The mRNA levels of all four genes peak in the subjective morning as is the case with previously identified ccgs.
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