ReviewBMJ (Clinical research ed.)2001
Premature discontinuation of clinical trial for reasons not related to efficacy, safety, or feasibility.
Review in BMJ (Clinical research ed.), 2001. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
34 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- The Influence of Industry Affiliation on Randomized Controlled Trials of Platelet-Rich Plasma for Knee Osteoarthritis.The American journal of sports medicine · 2023Pooled it
- Industry and evidence-based medicine: Believable or conflicted? A systematic review of the surgical literature.Canadian journal of surgery. Journal canadien de chirurgie · 2011Pooled it
- Anti-interleukin-1 treatment in patients with rheumatoid arthritis and type 2 diabetes (TRACK): A multicentre, open-label, randomised controlled trial.PLoS medicine · 2019Trial
- Odon device for instrumental vaginal deliveries: results of a medical device pilot clinical study.Reproductive health · 2018Trial
- Would tirofiban have been shown non-inferior to abciximab had the TENACITY trial not been terminated for financial reasons?Journal of interventional cardiology · 2013Trial
- Discontinuation and nonpublication of osteosarcoma clinical trials: a cross-sectional analysis of ClinicalTrials.gov data.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2026Observational
- Publication Rate and Discontinuation Percentage of Registered Trials Involving Rotator Cuff Pathology.Orthopaedic journal of sports medicine · 2026Article
- How Can Pharmacology Help Us Overcome the Challenges of Drug Repositioning as Antivirals to Treat Emerging Pathogens? The Example of Covid-19.Clinical and translational science · 2026Review
- Reply to: Critical evaluation of the ProfiLER-02 study design and outcomes.Nature medicine · 2025Article
- Augmenting Insufficiently Accruing Oncology Clinical Trials Using Generative Models: Validation Study.Journal of medical Internet research · 2025Article
- Discontinuation and nonpublication of clinical trials in orthopaedic oncology.Journal of orthopaedic surgery and research · 2024Article
- Public reporting of black participation in anti-hypertensive drug clinical trials.American heart journal · 2023Article
- Rates of discontinuation and non-publication of upper and lower extremity fracture clinical trials.Journal of orthopaedic surgery and research · 2023Article
- Proceedings from the 3rd European Clinical Consensus Conference for clinical trials in device-based hypertension therapies.European heart journal · 2020Article
- Rates of Discontinuation and Nonpublication of Head and Neck Cancer Randomized Clinical Trials.JAMA otolaryngology-- head & neck surgery · 2020Article
- Trends in mental health clinical research: Characterizing the ClinicalTrials.gov registry from 2007-2018.PloS one · 2020Article
- Implications of product withdrawal on a post-approval pragmatic trial: The VOLUME study experience.Contemporary clinical trials communications · 2019Article
- Discontinued Drugs for the Treatment of Cardiovascular Disease from 2016 to 2018.International journal of molecular sciences · 2019Review
- Ryanodine Receptor 1-Related Myopathies: Diagnostic and Therapeutic Approaches.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2018Review
- Factors associated with clinical trials that fail and opportunities for improving the likelihood of success: A review.Contemporary clinical trials communications · 2018Review
Corrections and comments
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Authors and funding
13 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
PubMed holds no abstract for this paper.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.