ArticleGenome research2001
Generation of a high-density rat EST map.
Article in Genome research, 2001. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
15 citing papers in PubMed, 32 citations in OpenAlex.
- Detection of low-abundant novel transcripts in mouse hematopoietic stem cells.Molecular genetics and genomics : MGG · 2009Article
- Annotation of expressed sequence tags for the East African cichlid fish Astatotilapia burtoni and evolutionary analyses of cichlid ORFs.BMC genomics · 2008Article
- Development of a deer mouse whole-genome radiation hybrid panel and comparative mapping of Mus chromosome 11 loci.Mammalian genome : official journal of the International Mammalian Genome Society · 2006Article
- Chromosome bin map of expressed sequence tags in homoeologous group 1 of hexaploid wheat and homoeology with rice and Arabidopsis.Genetics · 2004Article
- A chromosome bin map of 2148 expressed sequence tag loci of wheat homoeologous group 7.Genetics · 2004Article
- Single nucleotide polymorphisms associated with rat expressed sequences.Genome research · 2004Article
- High-density rat radiation hybrid maps containing over 24,000 SSLPs, genes, and ESTs provide a direct link to the rat genome sequence.Genome research · 2004Article
- Integrative genomics: in silico coupling of rat physiology and complex traits with mouse and human data.Genome research · 2004Article
- Integration of the rat recombination and EST maps in the rat genomic sequence and comparative mapping analysis with the mouse genome.Genome research · 2004Article
- Integrated and sequence-ordered BAC- and YAC-based physical maps for the rat genome.Genome research · 2004Article
- FTIR spectroscopy demonstrates biochemical differences in mammalian cell cultures at different growth stages.Biophysical journal · 2003Article
- Gene discovery in the apicomplexa as revealed by EST sequencing and assembly of a comparative gene database.Genome research · 2003Article
- The LN54 radiation hybrid map of zebrafish expressed sequences.Genome research · 2001Article
- Automated construction of high-density comparative maps between rat, human, and mouse.Genome research · 2001Article
- Evolution of mammalian genome organization inferred from comparative gene mapping.Genome biology · 2001Review
Corrections and comments
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Authors and funding
15 authors at 1 institution in 2 countries.
Funding
Abstract
We have developed a high-density EST map of the rat, consisting of >11,000 ESTs. These ESTs were placed on a radiation hybrid framework map of genetic markers spanning all 20 rat autosomes, plus the X chromosome. The framework maps have a total size of approximately 12,400 cR, giving an average correspondence of 240 kb/cR. The frameworks are all LOD 3 chromosomal maps consisting of 775 radiation-hybrid-mapped genetic markers and ESTs. To date, we have generated radiation-hybrid-mapping data for >14,000 novel ESTs identified by our Rat Gene Discovery and Mapping Project (http://ratEST.uiowa.edu), from which we have placed >11,000 on our framework maps. To minimize mapping errors, ESTs were mapped in duplicate and consensus RH vectors produced for use in the placement procedure. This EST map was then used to construct high-density comparative maps between rat and human and rat and mouse. These maps will be a useful resource for positional cloning of genes for rat models of human diseases and in the creation and verification of a tiling set of map order for the upcoming rat-genome sequencing.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.