ArticleJournal of muscle research and cell motility2000
Jaw-closing muscles of kangaroos express alpha-cardiac myosin heavy chain.
Article in Journal of muscle research and cell motility, 2000. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 30 citations in OpenAlex.
- Research into the physiology of myosins - a personal odyssey.European journal of translational myology · 2025Article
- Behavioral correlates of fascicular organization: The confluence of muscle architectural anatomy and function.Anatomical record (Hoboken, N.J. : 2007) · 2025Review
- Jaw-Muscle Structure and Function in Primates: Insights Into Muscle Performance and Feeding-System Behaviors.Evolutionary anthropology · 2025Review
- Developmental, Physiological and Phylogenetic Perspectives on the Expression and Regulation of Myosin Heavy Chains in Craniofacial Muscles.International journal of molecular sciences · 2024Review
- The influence of jaw-muscle fibre-type phenotypes on estimating maximum muscle and bite forces in primates.Interface focus · 2021Article
- The ancient sarcomeric myosins found in specialized muscles.Skeletal muscle · 2019Review
- Expression of masticatory-specific isoforms of myosin heavy-chain, myosin-binding protein-C and tropomyosin in muscle fibers and satellite cell cultures of cat masticatory muscle.The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society · 2010Article
- Sarcomeric myosin expression in the tongue body of humans, macaques and rats.Cells, tissues, organs · 2010Article
- Masticatory (;superfast') myosin heavy chain and embryonic/atrial myosin light chain 1 in rodent jaw-closing muscles.The Journal of experimental biology · 2009Article
- Heterogeneity of alpha-cardiac myosin heavy chains in a small marsupial, Antechinus flavipes, and the effect of hypothyroidism on its ventricular myosins.Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology · 2008Article
- Developmental changes in ventricular myosin isoenzymes of the tammar wallaby.Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology · 2007Article
- Marsupial cardiac myosins are similar to those of eutherians in subunit composition and in the correlation of their expression with body size.Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology · 2007Article
- Cross-bridge kinetics of fast and slow fibres of cat jaw and limb muscles: correlations with myosin subunit composition.Journal of muscle research and cell motility · 2007Article
- Myosin isoforms and fibre types in jaw-closing muscles of Australian marsupials.Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology · 2006Article
- Postnatal transitions in myosin heavy chain isoforms of the rabbit superficial masseter and digastric muscle.Journal of anatomy · 2006Article
- Functional properties of skinned rabbit skeletal and cardiac muscle preparations containing alpha-cardiac myosin heavy chain.Pflugers Archiv : European journal of physiology · 2004Article
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The masseter muscle of eutherian grazing mammals typically express beta or slow myosin heavy chain (MyHC). Myosins in the masseter of 4 species of kangaroos and a slow limb muscle of one of them were compared with their cardiac myosin by pyrophosphate and sodium dodecyl sulphate (SDS) gel electrophoresis, immunoblotting and immunohistochemistry. It was found that ventricular muscle contains three isoforms homologous to V1 (alpha-MyHC homodimer), V2 (heterodimer) and V3 (beta-MyHC homodimer) of eutherian cardiac muscle, and that the masseter contained V1, with traces of V2 and V3, in great contrast to eutherian ruminants, which express only V3. A polyclonal antibody (anti-KJM) was raised in rabbits against red kangaroo masseter myosin. After cross-absorption against limb muscle myofibrils, anti-KJM specifically reacted in Westerns with MyHCs from masseter but not limb muscles, and immunohistochemically with masseter, but not limb muscle fibers. In pyrophosphate Western blots, anti-KJM reacted with V1 but not with V3. However, a monoclonal antibody specific for eutherian slow myosin stained all kangaroo slow muscle fibers but only weakly stained scattered fibers in the masseter. The SDS-PAGE revealed that light chain composition of masseter and ventricular myosins is identical, but isoforms of both light chains of kangaroo limb slow myosin were observed. These results confirm that kangaroo jaw muscle express alpha-MyHC rather than beta-MyHC. The difference in MyHC gene expression between marsupial and eutherian grazers may be related to the fact that kangaroos are not ruminants, and have only a single chance to comminute food into fine particles, hence the need for the greater speed and power of muscle contraction associated with V1 containing muscle fibers.
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