ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2001
Differential expression of synaptic and nonsynaptic mechanisms underlying stimulus-induced gamma oscillations in vitro.
Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2001. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
16 citing papers in PubMed, 49 citations in OpenAlex.
- Simulation of oscillatory dynamics induced by an approximation of grid cell output.Reviews in the neurosciences · 2023Review
- The Unexplored Territory of Neural Models: Potential Guides for Exploring the Function of Metabotropic Neuromodulation.Neuroscience · 2021Review
- 5-Hydroxytryptamine1A receptor-activation hyperpolarizes pyramidal cells and suppresses hippocampal gamma oscillations via Kir3 channel activation.The Journal of physiology · 2014Article
- Chronic stimulation of cultured neuronal networks boosts low-frequency oscillatory activity at theta and gamma with spikes phase-locked to gamma frequencies.Journal of neural engineering · 2012Article
- Amygdalocortical circuitry in schizophrenia: from circuits to molecules.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2010Review
- Distributed processing and temporal codes in neuronal networks.Cognitive neurodynamics · 2009Article
- Detecting seizure origin using basic, multiscale population dynamic measures: preliminary findings.Epilepsy & behavior : E&B · 2009Review
- Circuitry-based gene expression profiles in GABA cells of the trisynaptic pathway in schizophrenics versus bipolars.Proceedings of the National Academy of Sciences of the United States of America · 2008Article
- Region-specific changes in gamma and beta2 rhythms in NMDA receptor dysfunction models of schizophrenia.Schizophrenia bulletin · 2008Review
- Stimulus-dependent oscillations and evoked potentials in chinchilla auditory cortex.Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology · 2008Article
- Gamma oscillatory firing reveals distinct populations of pyramidal cells in the CA1 region of the hippocampus.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2008Article
- Layer-specific pyramidal cell oscillations evoked by tetanic stimulation in the rat hippocampal area CA1 in vitro and in vivo.The Journal of physiology · 2005Article
- Carbonic anhydrase isoform VII acts as a molecular switch in the development of synchronous gamma-frequency firing of hippocampal CA1 pyramidal cells.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2004Article
- Fast network oscillations induced by potassium transients in the rat hippocampus in vitro.The Journal of physiology · 2002Article
- Self-organized synaptic plasticity contributes to the shaping of gamma and beta oscillations in vitro.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2001Article
- Gamma oscillation underlies hyperthermia-induced epileptiform-like spikes in immature rat hippocampal slices.BMC neuroscience · 2001Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
Gamma frequency oscillations occur in hippocampus in vitro after brief tetani delivered to afferent pathways. Previous reports have characterized these oscillations as either (1) trains of GABA(A) inhibitory synaptic events mediated by depolarization of both pyramidal cells and interneurons at least in part mediated by metabotropic glutamate and acetylcholine receptors, or (2) field potential oscillations occurring in the near absence of an inhibitory synaptic oscillation when cells are driven by depolarizing GABA responses and local synchrony is produced by field effects. The aim of this study was to investigate factors involved in the differential expression of these synaptically and nonsynaptically gated oscillations. Field effects were undetectable in control recordings but manifested when slices were perfused with hypo-osmotic solutions or a reduced level of normal perfusate. These manipulations also reduced the amplitude of the train of inhibitory synaptic events associated with an oscillation and enhanced the depolarizing GABA component underlying the post-tetanic depolarization. The resulting field oscillation was still dependent, at least in part, on inhibitory synaptic transmission, but spatiotemporal aspects of the oscillation were severely disrupted. These changes were also accompanied by an increase in estimated [K(+)](o) compared with control. We suggest that nonsynaptic oscillations occur under conditions also associated with epileptiform activity and constitute a phenomenon that is distinct from synaptically gated oscillations. The latter remain a viable model for in vivo oscillations of cognitive relevance.
Indexed as
Identifiers
11222662PMC6762952W2167859804What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.