ArticleJournal of bacteriology2001
Involvement of ResE phosphatase activity in down-regulation of ResD-controlled genes in Bacillus subtilis during aerobic growth.
Article in Journal of bacteriology, 2001. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 29 citations in OpenAlex.
- Shedding light on YfhS and YjlC: novel effectors of the NADH dehydrogenase activity of the electron transport chain inbioRxiv : the preprint server for biology · 2026Article
- Transcriptional and Post-transcriptional Control of the Nitrate Respiration in Bacteria.Frontiers in molecular biosciences · 2021Review
- Phosphatase activity of the control of virulence sensor kinase CovS is critical for the pathogenesis of group A streptococcus.PLoS pathogens · 2018Article
- Mixomics analysis of Bacillus subtilis: effect of oxygen availability on riboflavin production.Microbial cell factories · 2017Article
- Adaptation inFrontiers in microbiology · 2016Review
- In vivo characterization of the scaffold activity of flotillin on the membrane kinase KinC of Bacillus subtilis.Microbiology (Reading, England) · 2015Article
- The two-component sensor KinB acts as a phosphatase to regulate Pseudomonas aeruginosa Virulence.Journal of bacteriology · 2012Article
- Genetic and biochemical dissection of a HisKA domain identifies residues required exclusively for kinase and phosphatase activities.PLoS genetics · 2012Article
- Kinetic characterization of the WalRKSpn (VicRK) two-component system of Streptococcus pneumoniae: dependence of WalKSpn (VicK) phosphatase activity on its PAS domain.Journal of bacteriology · 2010Article
- How important is the phosphatase activity of sensor kinases?Current opinion in microbiology · 2010Review
- Input output robustness in simple bacterial signaling systems.Proceedings of the National Academy of Sciences of the United States of America · 2007Article
- Control of enterotoxin gene expression in Bacillus cereus F4430/73 involves the redox-sensitive ResDE signal transduction system.Journal of bacteriology · 2006Article
- The Fnr regulon of Bacillus subtilis.Journal of bacteriology · 2006Article
- Mutational analysis of the signal-sensing domain of ResE histidine kinase from Bacillus subtilis.Journal of bacteriology · 2004Article
- Functional analysis of the Mycobacterium tuberculosis MprAB two-component signal transduction system.Infection and immunity · 2003Article
- Physiological characterization of a heme-deficient mutant of Staphylococcus aureus by a proteomic approach.Journal of bacteriology · 2003Article
- Induction of ResDE-dependent gene expression in Bacillus subtilis in response to nitric oxide and nitrosative stress.Journal of bacteriology · 2002Article
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The ResD-ResE signal transduction system is required for aerobic and anaerobic respiration in Bacillus subtilis. The histidine sensor kinase ResE, by functioning as a kinase and a phosphatase for the cognate response regulator ResD, controls the level of phosphorylated ResD. A high level of phosphorylated ResD is postulated to cause a dramatic increase in transcription of ResDE-controlled genes under anaerobic conditions. A mutant ResE, which retains autophosphorylation and ResD phosphorylation activities but is defective in ResD dephosphorylation, allowed partially derepressed aerobic expression of the ResDE-controlled genes. The result indicates that phosphatase activity of ResE is regulated by oxygen availability and anaerobic induction of the ResDE regulon is partly due to a reduction of the ResE phosphatase activity during anaerobiosis. That elimination of phosphatase activity does not result in complete aerobic derepression suggests that the ResE kinase activity is also subject to control in response to oxygen limitation.
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