ArticleBiophysical journal2001
Optical anisotropy in lipid bilayer membranes: coupled plasmon-waveguide resonance measurements of molecular orientation, polarizability, and shape.
Article in Biophysical journal, 2001. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
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Who cites it
30 citing papers in PubMed, 172 citations in OpenAlex.
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- Plasmon Waveguide Resonance: Principles, Applications and Historical Perspectives on Instrument Development.Molecules (Basel, Switzerland) · 2021Review
- Plasmonic Optical Biosensors for Detecting C-Reactive Protein: A Review.Micromachines · 2020Review
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- Improved Detection of Plasmon Waveguide Resonance Using Diverging Beam, Liquid Crystal Retarder, and Application to Lipid Orientation Determination.Sensors (Basel, Switzerland) · 2019Article
- Biophysical Characterization of Supported Lipid Bilayers Using Parallel Dual-Wavelength Surface Plasmon Resonance and Quartz Crystal Microbalance Measurements.Langmuir : the ACS journal of surfaces and colloids · 2018Article
- Label-free nanoscale optical metrology on myelinated axons in vivo.Nature communications · 2017Article
- Localization accuracy of gold nanoparticles in single particle orientation and rotational tracking.Optics express · 2017Article
- Examination of the Interaction between a Membrane Active Peptideand Artificial Bilayers by Dual Polarisation Interferometry.Bio-protocol · 2017Article
- Molecular organization, localization and orientation of antifungal antibiotic amphotericin B in a single lipid bilayer.Scientific reports · 2016Article
- Enhancing the detection limit of nanoscale biosensors via topographically selective functionalization.Analytical chemistry · 2014Article
- Molecular interaction of a new antibacterial polymer with a supported lipid bilayer measured by an in situ label-free optical technique.International journal of molecular sciences · 2013Article
- Using complementary acoustic and optical techniques for quantitative monitoring of biomolecular adsorption at interfaces.Biosensors · 2012Review
- Nanodisc-based co-immunoprecipitation for mass spectrometric identification of membrane-interacting proteins.Molecular & cellular proteomics : MCP · 2011Article
- New trends in instrumental design for surface plasmon resonance-based biosensors.Biosensors & bioelectronics · 2011Review
- Broadband plasmon waveguide resonance spectroscopy for probing biological thin films.Applied spectroscopy · 2009Article
- Plasmon-waveguide resonance studies of ligand binding to integral proteins in membrane fragments derived from bacterial and mammalian cells.Analytical biochemistry · 2009Article
- Reconstitution of rhodopsin into polymerizable planar supported lipid bilayers: influence of dienoyl monomer structure on photoactivation.Langmuir : the ACS journal of surfaces and colloids · 2008Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The birefringence and linear dichroism of anisotropic thin films such as proteolipid membranes are related to molecular properties such as polarizability, shape, and orientation. Coupled plasmon-waveguide resonance (CPWR) spectroscopy is shown in the present work to provide a convenient means of evaluating these parameters in a single lipid bilayer. This is illustrated by using 1-10 mol % of an acyl chain chromophore-labeled phosphatidylcholine (PC) incorporated into a solid-supported PC bilayer deposited onto a hydrated silica surface. CPWR measurements were made of refractive index and extinction coefficient anisotropies with two exciting light wavelengths, one of which is absorbed by the chromophore and one of which is not. These results were used to calculate longitudinal and transverse molecular polarizabilities, the orientational order parameter and average angle between the longitudinal axis of the lipid molecule and the membrane normal, and the molecular shape factors of the lipid molecules. The values thereby obtained are in excellent agreement with parameters determined by other techniques, and provide a powerful tool for analyzing lipid-protein, protein-protein, and protein-ligand interactions in proteolipid films.
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